Back issues No.4 - 1988  
  Original Study
  Evaluation of Prostaglandin and Thromboxane Plasma Levels in Blackfoot Disease Patients
Gwo-Shing Chen, Hsin-Su Yu, Ying-Chin Kao, Ching-Chun Pan, Bing-Rong Tserng, Jaw-Shin Kao, Kan-Tang Fang
Dermatol Sinica 6: 205-212, 1988

Plasma levels of 6-keto-prostaglandin Flα(6-keto-PGF1α) and thromboxane B2 (TX B2) in 28 Blackfoot Disease patients (20 males, and 8 females, aged 36-80 years) in Taiwan prefecture were studied. The same numbers of normal controls were chosen from the same endemic area (20 males and 8 females, aged 48-89 years) and the Kaohsiung area (20 males and 8 females, aged 39-76 years).The 6-keto-PGF1αand TX B2 plasma levels were determined by radioimmunoassay. The results showed the levels of 6-keto-P ..................More
  Case Report
  Juvenile Colloid Milium
Tsu-Chyang Chen, Chang-Lin Chen, Chu-Kwang Wong
Dermatol Sinica 6: 213-219, 1988

A case of juvenile colloid milium was presented. Clinically, pinkish, translucent papules were found on the right face and the extensor site of her left arm. Histochemically , PAS-positive colloid material accumulated massively in the epidermis. In electron microscopy, colloid material showed a fine granular structure, but had no characteristics of amyloid, The skin lesions responded well to topical retinoic acid (0.05% Tretinoin). No recurrence has been noted since then. ..................More
  Perforating Disease in Chronic Renal Failure
I-Hsin Shih, Shin-Yueh Chen, Yue-Zon Kuan, Tseng-Tong Kuo
Dermatol Sinica 6: 221-228, 1988

A case of perforating skin disease in a diabetic patient with renal failure is reported. Keratotic papules devloped on his back and four extremities two months prior to hemodialysis. Histopathologically, parakeratotic plugs extended to the basal layer with epidermal thinning and perforation. Transepithelial elimination of the collagen fibers are observed. These features are shared by Kyrle's disease and reactive perforating collagenosis, but do not fit either entity totally. So the term "pe ..................More
  Ano-sacral Cutanous Amyloidosis
Jen-Hong Yang, Chu-Kwan Wong
Dermatol Sinica 6: 229-236, 1988

Ano-sacral cutaneous amyloidosis is an uncommon prsentation of primary cutaneous amyloidoses. We report a case of ano-sacral cutaneous amyloidosis with an unusual clinical manifestations. The diagnosis is confirmd by histochemical and electron microscopical studies. We also discuss the possible etiologies, pathogenesis and diagnosis of primary cutaneous amyloidoses. ..................More
  Dermatofibrosarcoma Protuberans - A Clinical Analysis of 18 Coases
Ying-Chei Tsai, Hsu-Po Yeh
Dermatol Sinica 6: 237-246, 1988

Dermatofibrosarcoma protuberans is a rare, localized, low grade sarcoma originating in the dermis and characterized by an unusually slow but invasive growth, a marked tendency to recur locally and infrequent metastasis. We review 18 cases of histopathologically proved dermatofibrosarcoma protuberans in NTUH from 1978 to 1987 and compare in detail the clinical and morphologic correlation with previous literature. The age of onset ranged from birth to 78 years of age, with most patients between ..................More
  Annular Elastolytic Giant Cell Granuloma - A Case Report -
Chih-Cheng Chang, Hsu-Po Yeh
Dermatol Sinica 6: 247-252, 1988

We describe a typical case of annular elastolytic giant cell granuloma (AEGCG) which was first reported in Taiwan. A 54-year-old wonman presented on her forehead several asymptomatic, annular, brownish red patches which had elevated borders and hypopigmented, slightly atrophic centers. Histopathology reveald a granulomatous infiltrate in the elevated border of the lesion and loss of elastic fibers in the center of the lesion. Differentiation between other entities presenting annular facial le ..................More
  Cheilitis Granulomatosa- A Case Report and Review of Literature
Lui-Lung Shen, Gwo-Jenn Leu, Wei-Min Li
Dermatol Sinica 6: 253-260, 1988

A 53-year-old female has developed persistent asymptomatic swelling of the lips for 7 months. On physical examination, both lips were normal in color, moderately firm, non-tender and diffuse swollen. Oral cavity revealed poor hygiene, erythematous swollen gum with moderate generalized periodontitis, and ill-fitted crowns and bridges. A biopsy from the lower lip showed multiple noncaseous epithelioid granulomas with chronic inflammatory cell infiltration in the dermis. There were no evidence ..................More
  Thromboangiitis Obliterans (Buerger's Disease) Associated with Thrombophlebitis Migrans- A Case Report -
Ming-Tsann Wang, Hsin-Su Yu, Jaw-Shin Kao, Gwo-Shin Chen, Tsu-Chieh Schen
Dermatol Sinica 6: 261-268, 1988

A 23 years old male patient, had smoking history for 5 years, sufferred from tingling and cyanosis on left big toe for 6 months. Intermittent claudication and thrombophlebitis migrans also was noted. Histopathology of skin biopsy showd that a thrombus occluded the lumen and inflammatory cells permeated the vessel wall of a large vein in lower dermis. Left iliofemoral arteriography demonstrated patent of iliac, femoral and popliteal arteries, but occlusion of anterior and posterior arteries. ..................More
  Congenital Smooth Muscle Hamartoma- A Case Report -
Ja-Shin Lin, Chen-Nai Wang, Ming-Jing Chen, Yue-Zon Kuan, Tseng-Tong Kuo
Dermatol Sinica 6: 269-274, 1988

Congenital smooth muscle hamartoma is a rare benign condition of the skin characterized by a proliferation of large bundles of non-striated muscle fibers in the recticular dermis. They typically appear as flesh-colored or mildly hyperpigmented patches or elevated plaques, usually with a variable amount of hypertrichosis of the overlying skin. In this report, we describe a casee of congenital smooth muscle hamartoma with follicular hyperpigmented macules. This is a rare clinical form of congen ..................More
  Keratosis Follicularis Complicated with Eczema Herpeticum - A Case Report with Discussion on Neurologic and Psychiatric Side-effects of Acyclovir
Yi-Tuen Chung, Herng-Ming Leu, Ruey-Yi Lin, Hwei-Wen Lee
Dermatol Sinica 6: 275-280, 1988

An 18 years old male patient who was a case of familial keratosis follicularis trated with etretinate developed eczema herpeticum for three times. In the first two episodes, he was treated with oral acyclovir and developed psychotic reaction including incoherent speech and paranoid condition. Electroencephalography also showed diffuse slow waves. The reaction subsided without evidnt sequela after discontinuing acyclovir and adequate therapy. ..................More
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