Back issues No.1 - 1989  
  Methotrexate in Dermatology
Kevin C. Smith, W. P. Daniel Su, Sigfrid A. Muller
Dermatol Sinica 7: 11-18, 1989

Methotrexate (MTX) is a useful medication in treating severe cases of psoriasis and psoriatic arthritis. It is also a good adjuvant therapeutic agent for many other dermatoses if they do not respond to regular treatment. However, it is a drug with multiple potential side effects. Therefore, one must be familiar with the following aspects of MTX: mode of action, pharmacokinetics, interactions with other drugs, side effects, and contraindications. We present the guidelines used int he Departeme ..................More
  Original Study
  A Recent Study on Dermatophytoses and Their Etiologic Agents in Taichung, Taiwan,R.O.C.
Tse-Hsun Huang, Shih-Fu Cheng, John C. Tsauhong
Dermatol Sinica 7: 1-6, 1989

Between March and June 1988, 113 patients suspected having dermatophytoses were selected from the out-patient clinic of Dermatology at China Medical College Hospital for surveillance of etiological agents. A total of 138 specimens was collected from 6 various anatomical sites for fungal cultrue. Among them, threee species of dermatophytes namely Trichophyton urbrum, Trichophyton mentagrophytes and Epidermophyton floccosum, and some yeasts were isolated from 63 specimens of 52 patients. ..................More
  Cutaneous Horn:Clinical and Histopathological Analysis of 20 Cases
Li-Fang Wang, Hsu-Po Yeh, Yau-Chin Lu
Dermatol Sinica 7: 7-10, 1989

Cutaneous horn is a symptomatic nomenclature. It could be arising from various underlying processes that may be benign, premalignant or malignant. The histopathological review of cutaneous horn in National Taiwan University Hospital from 1981 to 1987 revealed that five among all of twenty cases were premalignant or malignant. It emphasizes that cutaneous horn arising from malignancy is not uncommon. So, every case of cutaneous horn must be excised and sent for histopathological study. ..................More
  Case Report
  Penicilliosis Caused by Penicillium Marneffei-A Case Report-
I-Li Wang, Hsu-Po Yeh, Shan-Chwen Chang, Jau-Shiuh Chen
Dermatol Sinica 7: 19-22, 1989

We report a 44-year-old female with penicilliosis who had some pea-sized papules over the scalp, face, chest and buttocks which ulcerated spontaneously to form punch-out skin lesions and who also had other systemic signs including fever, general malaise, productive cough, cervical lymphadenopathy. In addition a hen-egg sized hazziness with a central cavity at the right hilum was revealed by chest x-ray. Biopsies taken from both a skin lesion and the lymph node showed the presence of many yeast- ..................More
  Nontuberculous Scrofuloderm-A Case Report-
Bing-Hwang Lin, Hsu-Po Yeh
Dermatol Sinica 7: 23-27, 1989

Atypical mycobacteria are a heterogenous group of microorganisms which are being implicated with increasing frequency as the cause of infection in human. A case of nontuberculous scrofuloderma caused by Mycobacterium scrofulaceum is reported and the literature reviewed. The patient, a 44-yar-old worker, developed multiple ulcers and sinuses on the cheeks, lateral aspects of the neck and the upper chest for 4 years. The clinical picture closely mimiced tuberculous scrofuloderma and the cellula ..................More
  Epidermolysis Bullosa Acquisita Diagnosed by Indirect Immunopatological Method
Wen-Yu Liao, Ying-Chin Wu, Hsien-Ching Chiu
Dermatol Sinica 7: 29-34, 1989

A 35 year-old female patient with a three-month history of generalized bullous eruption is described. Clinical, histologic, and immuno-fluorescence findings resembled bullous pemphigoid, but using indirect immuno-fluorescence on 1N NaC1 separated normal skin, the fluorescence was detected at the dermal side; thus, the differential diagnosis of epidermolysis bullosa acquisita from bullous pemphigoid was easily made. ..................More
  Cutis Marmorata Telangiectatica Congentia
Chung-Dar Liao, Charng-Shi Lin, Siew-Khon Ooi, I-Wen Shieh, Ren-Bin Tang
Dermatol Sinica 7: 35-39, 1989

Cutis marmorata telangiectatica congenita (CMTC) is an extremely rare congenital skin disease. It was first descried by Van Lohuizen in 1922 and was characterized by (1) telangiectasia and phlebectasia associated with cutis marmorata pattern. (2) frequent association with other congenital abnormalities (3) a tendency to improve with age in some cases, especially in the first two years. We reported herein a mal newborn case of CMTC who developed marmorata-like telangiectasia and phlebectasia wi ..................More
  Sclerosing Sweat Duct Carcinoma-A Case Report-
Chun-Jae, Heng-Leong Chan, Yue-Zon Kuan, Tseng-Tong Kuo
Dermatol Sinica 7: 41-46, 1989

A 56-year-old male presented with 2-year-history of several asympatomatic skin-colored and brownish nodules, 0.5-0.8 cm in size with smooth surface on interanl malleolar area of right foot. Histologic study revealed irregularly invasive clear-celled small nests or glandular structures in the dermis and subcutis with sclerotic change. The microscopic appearance is characteristic of a sclerosing sweat duct carcinoma. ..................More
  Kaposi's Scarcoma--A Case Report-
Fu-Gin Chu, Han-Nan Liu, The-Lu Chu, Horng-Lieh Sy, Hei-Haw Tzeng
Dermatol Sinica 7: 47-52, 1989

A 38 years old married male suffered from multiple asymptomatic brownish to purple papules over both soles and ankle regions for about one year. He denied any history of homosexuality. The laboratory data were normal. HIV test was negative. The histopathology study revealed classic kaposi's sarcoma. All lesions were surgically removed. ..................More
  Keratotic Scabies (Norwegian Scabies)-Four Cases Report and Literature Review
Lih-Jen Yang, Heng-Leong Chan, Ming-Jing Chen, Yue-Zon Kuan
Dermatol Sinica 7: 53-60, 1989

In this paper, we report four cases of keratotic scabies (Norwegian scabies) in three old ladies crippled by degenerative joint disease and in one comatous man suffered from meninoencephalitis of unknown eitology. One of the three ladies has definite iatrogenic Cushing's syndrome. Two episodes of small epidemic were found in the family members and in ward medical personnal. Follow-up one to seven months later showed no recurrence. A brief discussion on differential diagnosis, associated nail ..................More
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