Back issues No.3 - 1989  
  Original Study
  Histochemical and Ultrastructural Studies of Cutaneous Side Effects Due to Topical Corticosteroids - I. Changes in Epidermis
Hamm-Ming Sheu, Hsin-Su Yu, Tsu-Chieh Shen
Dermatol Sinica 7: 143-153, 1989

Histochemical, scanning and transmission electron microscopic studies were performed to examine the cutaneous side effects due to topical corticosteroids in 49 patients. The epidermal changes showed that,(1)the skin revealed loss of skin markings,(2)decrease of neutral lipids was obvious and loss of membrane-coating granules was also found,(3)keratin intermediate filaments of keratinocytes were sparce,(4)the number of melanocytes was slightly decreased; However, melanosomes were greatly decrease ..................More
  Case Report
  Linear IgA Disease of Adult
Jer-Hwang Chiou, Jyh-Jier Lii, Jui-Lung Shen, Wen-Jen Wang, Joung-Liang Lan
Dermatol Sinica 7: 155-161, 1989

Linear IgA disease of adult is now considered as a distinct entity, which is different from bullous pemphigoid and dermatitis herpetiformis by direct immunofluorescent demonstration of linear IgA deposits along the basement membrane zone. A 67-year-old female complained of generalized severe itch for two years. Physical examination revealed a few clusterend tiny vesicles on erythematous bases located on the back accompanied with generalized erosions, crusts and excoriations. There was no evidenc ..................More
  Depressed Dermatofibrosarcoma
Chun-I Chen, Shih-Yueh Chen, Yue-Zon Kuan, Tseng-Tong Kuo
Dermatol Sinica 7: 163-168, 1989

A 21-year-old female was suffered from a painful erythematous depressed lesion of 2.5×2.5 cm on her chest for ten years. The lesion was tender, erythematous, round and well-defined. Histopathologic study revealed a highly cellular dermal mass with infiltration into the subcutaneous fat layer, which was composed of spindle cells arranged in storiform pattern with a few atypia and mitosis, Histopathologically, it was indistinguishable from a dermatofibrosarcoma protuberans, but clinically it was ..................More
  Malignant Eccrine Poroma with Sarcomatoid Differentiation
Horng-Lieh Sy, Han-Nan Liu, Hui-Hwa Tseng, The-Chu, Yen-Chang Tu
Dermatol Sinica 7: 169-177, 1989

A 87-year-old female suffered from a brownish plaque with verrucous surface measuring 2.5×2.0 cm on the right thigh for one year. There was also one red mushroom-like nodule abut 2×1.5×1.5cm protruding from the margin of the aforementioned plaque. The pathological examination of the plaque showed a pattern of malignant eccrine poroma. However, a sarcoma-like pattern was disclosed in the mushroom-like nodule. The immunohistochemical studies revealed positive staining for both cytokeratin and v ..................More
  Neutrophilic Dermatosis of Myeloproliferative Disorders
Yu-Shung Lee, Chen-Nai Wang, Yue-Zon Kuan
Dermatol Sinica 7: 179-188, 1989

Sweet's syndrome, atypical sweet's syndrome, pyoderma gangrenosum, and bullous pyoderma gangrenosum have been separately reported in association with various forms of hematologic disorders oveer the past decade. Although the clinical lesions vary, these dermatoses have th same pathophysiologic phenomenon that they are reactive processes mediated by neutrophils. Recently, the term "neutrophilic dermatosis of myeloproliferative disorders" has been suggested for including these spectrum of skin les ..................More
  Balloon Cell Nevus Arising from A Large Congenital Melanocytic Nevus
Yue-Feng Wang, Yu-Chia Lee, Heng-Leong Chan, Ming-Jing Chen, Yue-Zon Kuan, Tseng-Tong Kuo
Dermatol Sinica 7: 189-194, 1989

We report a balloon cell nevus arising from a large congenital melanocytic nevus. To our knowledge, no similar case has been reported in the literature. The condition adds another differential diagnosis beside malignant melanoma, when a new growth from a congenital melanocytic nevus is eencountered. ..................More
  Extramammary Paget's Disease on the Scrotum
Yung-Shun Hsieh, Jin-Yuang Chen, Kan-Tang Fang
Dermatol Sinica 7: 195-199, 1989

A 58-year-old men was noted to have a well-defined erythematous plaque, measuring 5×6 cm, with oozing and crusting over right side of scrotum for 2 years. Pathology shwed many lightly stained large round cells scattered in the epidermis which were stained reddish with PAS-diastase and bluish with alcian blue. Related literatures are reviewed. ..................More
  Hair Casts - An Electron Microscopic Study
Yi-Huei Wang, I-Chung Hong, Alpha Cheng, Huei-Men Chen, Ko-Kaung Liao
Dermatol Sinica 7: 201-208, 1989

There are two types of hair casts. The uncommon type is peripilar keratin casts and the common one, parakeratotic hair casts. Clinically, the former reveals cylindrical appearance and there is no any skin disease at the underlying scalp. The latter shows irregular contour, and the underlying scalp skin is always associated with parakeratotic disorders. Ultrastructurally, both types are considerably different from each other. Investigations, including scanning and transmission electron microscopy ..................More
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