Back issues No.1 - 1990  
  Original Study
  Histochemical and Ultrasturctural Studies of Cutaneous Side Effects Due to Topical Corticosteroids - II. Changes in Dermal Connective Tissue
Hamm-Ming Sheu, Hsin-Su Yu, Tsu-Chieh Shen
Dermatol Sinica 8: 1-13, 1990

Histochemical, immunofluorescent, scanning and transmission electron microscopic studies were performed on cutaneous side effects of 49 patients dut to topical corticosteroids. The dermal connective tissue changes showed that (1)loss of ground substance and fibronectin were noted; (2) the fibers of upper dermis appeared compressed and became parallel to the skin surface, and a flat dermalepideraml interface was formed; (3) the cytoplasm of fibroblasts were markedly rduced with little organelles ..................More
  Case Report
  Secondary Syphilis with Jarisch-Herxheimer Reaction
Chang-Long Tai, Hsin-Su Yu, Tsu-Chieh Shen, Gwo-Shing Chen
Dermatol Sinica 8: 15-22, 1990

A 34-year-old male patient has had two erythematous flattn plapues on face and many reddish maculopapules on upper trunk which developed about 4 months after extramarital sexual exposure.Clinical course, biopsy findings and strong positive VDRL & TPHA disclosed a picture of "secondary syphilis".After the initial IM injection of 2.4 million units of benzathine penicillin G, generalized rose-red macules developed 3 hours later. Concurrent mild fever, headache & myalgia were also noted. The symp ..................More
  Malignant Acanthosis Nigricans with Stomach Adenocarcinoma and Esophageal Paailloma
Sen-An Yang, Hamm-Ming Sheu, Li-Tzong Chen, Hsin-Su Yu, Chang-Yi Chen
Dermatol Sinica 8: 23-29, 1990

We herein report a typical case of acanthosis nigricans (AN). A 74-year-old male patient suffered from pigmented and velvety skin changes on the neck, axilla and inguinal area for half a year. Disseminated florid cutaneous papillomatosis were noted on the whole body. After a series of examinations, adenocarcinoma of the stomach and papilloma of the esophagus were found. After receiving chemotherapy for three months, florid cutaneous papillomatosis made marked improvements. The size of adenocarci ..................More
  Pemphigus Foliaceus with Cryptococcemia Caused by Cryptococcus Albidus
Sen-An Yang, Shiu-Ru Lin, Hsin-Su Yu, Hamm-Ming Sheu, Chein-Fang Peng
Dermatol Sinica 8: 31-35, 1990

We report a case of pemphigus foliaceus with cryptococcemia. A 45-year-old male patient suffered from gneralized erythroderma and the results of histopathology and DIF revald intrapidermal acantholysis & positive epidermal intercellular fluorescence. Pemphigus foliaceus was diagnosed. After receiving treatment, fever and leukocytosis were noted. Accidentally, cryptococcmia was found by blood cultrue. Besides, Cryptococcus Ag Latex test titer was> =1:128. After API 20c Aux profile recognitio ..................More
  Giant Cell Tumor of Tendon Sheath
Ren-Chun Liao, Hsin-Yi Su, Yung-Fa Chao, Hsiu-Chin Chen, Hsu-Po Yeh
Dermatol Sinica 8: 37-40, 1990

Giant cell tumor of tendon sheath is a common benign tumor of tendon sheaths and joints or synovium. We herein report a localized giant cell tumor of tendon sheath (nodular tenosynovitis) which occurred on right little finger of a 36-year-old female. Histopathology reveals proliferation of round or polygonal cells(synovial-like cells), intermingled with multinucleated giant cells, hemosiderinladen cells and foam cells. Aggressive local excision was perfrormed when recurrence was noted after t ..................More
  Sebaceous Carcinoma Arising from Sebaceous Nevus
Si-Ming Chau, Min-Shin Yang, Tseng-Tong Kuo
Dermatol Sinica 8: 41-45, 1990

We report the first case of sebaceous carcinoma arising from nevus sbaceus. A 48-year-old man noted a luster of waxy papules on his parietal scalp for about 30years.Some of the papules enlarged rapidly in the past six-months. The enlarged mass was proved histopathologically to be sebaceous carcinoma and the surrounding papuls were nevus sebaceus. The lesion was totally excised. There was no evidence of recurrence of the tumor within half year of follow up. ..................More
  Scleredema Adultorum
Jin-Yuang Chen, Kan-Tang Fang
Dermatol Sinica 8: 47-51, 1990

A 75-year-old male suffered from nopitting induration of skin of posterior aspect of neck and upper back with decreased skin folds and erythematous patch for four months. The patient has no history of diabetes mellitus or precding respiratory tract infection. Skin pathology showed increased interfibrillar space, and staining with alcian blue at pH 2.5 revealed positive result. Under the diagnosis of scleredema adultorum, he received topical steroid ointement using occlusive dressing therapy w ..................More
  Angiokeratoma Circumscriptum
Jly-Ming Hong, Tse-Hsun Huang, Sai-Foo Cheng
Dermatol Sinica 8: 53-59, 1990

A 17-year-old male had presented with a slowly enlarging verrucous purpuric plaque measuring 6*6 cm at its greatest dimension for 11 years with occasional tenderness on extermal malleolar area of right foot. Histopathologic examination revealed groups of superficial, ectatic, thin-walled vessels covered by hyperkeratotic epidermis, Based on the clinicohistologic findings, this is a case of angiokeratoma circumscriptum. ..................More
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