Back issues No.4 - 1996  
  Original Study
  The Recovery of Skin Physiologic Functions After Selective Removal of Stratum Corneum Lipids from Forearm Skin
Lien-Chun Chin, Chiun-Hsing Chang, Gwo-Shing Chen, Hsin-Su Yu
Dermatol Sinica 14: 207-215, 1996

The recovery of skin physiologic functions including transepidermal water loss (TEWL), skin hydration, water-holding capacity, skin surface pH, casual sebum amount, cutaneous blood flow, and skin elasticity after selective removal of stratum corneum lipids from forearm skin of thirthy-nine healthy women were investigated. The stratum corneum lipids were removed using cup method by n-hexane/methanol and the extracted lipids were then separated using HPTLC. The measurements of the parameters of sk ..................More
  Case Report
  Castlemans Disease Associated with Pemphigus Vulgaris
Ke-Ti Chiang, Hsu-Po Yeh, Tak-Wah Wong, Shy-Shyun Liu
Dermatol Sinica 14: 216-222, 1996

Castleman's disease is a rare lymphoproliferative disorder and may be related to autoimmune diseases. Here we report a case of Castleman's disease associated with pemphigus vulgaris. A 16-year-old female was admitted because of diffuse painful erosions over buccal mucosa and lips. Physical examination revealed a giant cervical mass (7 x 5 x 3 cm in size) in the right supraclavicular area. This asymptomatic, slowly growing mass was noted for seven years. The oral lesions were diagnosed as pemphig ..................More
  Mycosis Fungoides Presenting Initially as Cutaneous Hypopigmentation
Yu-Wen Huang, Te-Hsuan Li, Tsen-Fang Tsai
Dermatol Sinica 14: 223-228, 1996

Hypopigmented, non-atrophic macules or patches are unusual manifestations of lesions of early mycosis fungoides. Presented herein is a with such lesions and was ever misdiagnosed as pityriasis alba and pityriasis versicolor. We review both the clinical and microscopic findings in this patient and in previously reported patients with hypopigmented lesions of mycosis fungoides. It is evident that the differential diagnosis of pityriasis alba should always include mycosis fungoides, as well as pity ..................More
  Benign Follicular Mucinosis
Lien-Chun Chin, Chiun-Hsing Chang, Gwo-Shing Chen, Hsin-Su Yu
Dermatol Sinica 14: 229-236, 1996

Follicular mucinosis is a primary idiopathic disorder, or it may be associated with benign or malignant diseases, particularly mycosis fungoids. A 15-year-old boy had one asymtomatic induration on his left preauricular area for one month. Skin biopsy showed mucinous degeneration in the outer root sheath and sebaceous gland, formation of cystic spaces, Mucicarmine stain and alcian blue stain (pH2.5) revealed acid mucopolysaccharides accumulation in the degenerated areas and cysitc spaces. Serial ..................More
  Nevoid Basal Cell Epithelioma Syndrome
Woan-Ruoh Lee, Hsu-Po Yeh, Jau-Shiuh Chen, Chung-Ren Tseng
Dermatol Sinica 14: 237-243, 1996

The nevoid basal cell epithelioma syndrome (NBCES) is a highly penetrative but variably expressed autosomal dominant disorder. The major manifestations are basal cell epitheliomas, odontogenic keratocysts, dyskeratotic pitting of the palms and soles and intracranial calcification as well as many other developmental skeletal anomalies. We report a typical case of a 34-year-old female patient with NBCES, showing basal cell epitheliomas on the scalp and forearm, bilateral odontogenic keratocysts, d ..................More
  Subcutaneous Phaeohyphomycosis Caused by Alternaria Species
Lin-Hui SU, Wen-Yu Liao, Tsen-Fang Tsai, Guang-Hsiang Hsiao, Hsien-Ching Chiu, Jiunn-Cherng Chen, Shiu-Feng Huang
Dermatol Sinica 14: 244-250, 1996

A 64-year-old farmer, who had diabetes mellitus and Cushing's syndrome, suffered from several skin lesions on extremities for one year. Physical examination revealed several eroded or crusted reddish brown plaques and nodules on both forearms, the left 4th finger, left lower leg, and dorsum of left foot. Histologically, it showed hyphal elements scattered in the suppurative granulomatous infiltrate in the dermis and subcutis. Fungal culture revealed a pigmented fungus with septate hyphae and cha ..................More
  Ichthyosis Linearis Circumflexa in Association with Trichorrhexis Invaginata
Jiunn-Yih Chen, J. Yu-Yun Lee, Chang-Long Tai
Dermatol Sinica 14: 251-257, 1996

Ichthyosis linearis circumflexa (ILC) Comel in association with trichorrhexis invaginata (TI) or bamboo hair is very rare and has not been reported in Taiwan. A 17 year-old young woman presented with a generalized erythema, scaling and fragility of the scalp hair since birth. The symptoms improved at puberty. Her two older sisters seemed suffered from similar skin disorders and died at young age. In recent one year, she developed several bouts of pustular lesions, and many polycyclic or serpigin ..................More
  POEMS Syndrome
Shih-Chung Ko, Gwo-Shing Chen, Ching-Ming Wang, Chung-Hsing Chang, Hsin-Su Yu
Dermatol Sinica 14: 258-262, 1996

POEMS (polyneuropathy、organomegaly、endocrinopathy、M-protein, and skin changes) syndrome is a multisystem disorder associated with plasma cell dyscrasia. Dermatologic changes may include hyperpigmentation, thickened skin, hypertrichosis、and papular angiomas. We report a female with typical POEMS syndrome who had plasma cell dyscrasia confirmed by open bone biopsy. Skin lesions showed hyperpigmentation, hypertrichosis and scleroderma. Skin thickening and sensory change in limbs improved gr ..................More
  Accessory Tragus on the Neck
Chin-Yuan Wang, Han-Nan Liu, Chu-Kwan Wong
Dermatol Sinica 14: 263-266, 1996

We herein report a typical case of accessory tragus on the neck. A 67-year-old male patient had an asymptomatic, firm, pedunculated nodule on the left anterior aspect of neck since childhood. Histopathologically, there are a central core of cartilage, a prominent connective tissue framework in the subcutaneous fat and numerous hair follicles. Accessory tragi are uncommon embryologic anomaly. They have many incorrect terms and are often overlooked as skin tags or fibromas. We emphasize its precis ..................More
  Segmental neurofibromatosis
Yu-Fu Chen, Zon Hsien Shih, Shau-Pai Shi, Chih-Ming Hung
Dermatol Sinica 14: 267-271, 1996

We report 3 patients with segmental NF, including one rare case with cutaneous neurofibromas localized on the upper back in a bilateral dermatomal distribution. Recent studies of the possible genetic mechanisms are also reviewed from the literature. ..................More
  Eccrine Poroma: A Report of a Dermal Variant
Chih-Hui Huang, Ke-Ming Hung
Dermatol Sinica 14: 272-275, 1996

A 45-year-old male presented with a brownish firm subcutaneous nodule on the right upper back. The pathological pictures showed various shaped tumor islands located in the dermis and composed of small, uniform, cuboidal cells. Ductal lumina and cystic spaces with some amorphous eosinophilic materials or calcified deposits were noted within some of the tumor islands. The histochemical studies revealed positive staining for the von-Kossa, PAS-diastase and alcian blue (pH 2.5) over the dermal duct ..................More
  Atypical Spitz Nevus
Su-In Hsu, Ching-Nan Lin
Dermatol Sinica 14: 276-279, 1996

This 9-year-old girl patient had a dome-shaped nodule on the right arm since birth that became enlarged recently and associated with surface ulceration. Pathologically the nodule showed closely packed lobules of spindle cells with cellular pleomorphism, atypia and high mitotic figures. The immunohistochemical stains showed positive staining of the spindle cells with S-100 protein, NSE and vimentin; stain for cytokeratin was negative. A diagnosis of atypical Spitz nevus was made on the basis of h ..................More
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