Back issues No.3 - 1997  
  Original Study
  Occupational Skin Diseases of Electronics Workers in Taiwan the Clinical manifestation and Causative Factors
Meng-Ying Hsieh, Yue-Liang Gue, Shu-Chu Shiao, Hamm-Ming Sheu
Dermatol Sinica 15: 147-156, 1997

The major processes of the electronics industry include the fabrication and assembly of semiconductors, printed circuit boards, and final products. Electronics factory workers are exposed to many irritants and allergens such as soldering fluxes, solvents, metals, and fiberglass, resulting in an increased risk of work-related skin disorders. We randomly surveyed 3070 workers from 5 large electronics factories in southern Taiwan by questionnaire to assess the prevalence of occupational dermatoses ..................More
  An Open Study to Compare the Efficacy and Tolerability of Terbinafine with Griseofulvin in Onychomycosis
Heng-Leong Chan, Li-Cheng Yang
Dermatol Sinica 15: 157-161, 1997

Griseofulvin has been regarded as a standard treatment of dermatophyte onychomycosis.1 The treatment of onychomycosis with griseofulvin are unsatisfactory due to low cure rate; in most infections, therapy must be prolonged with accompanying problems of patient compliance and treatment failure.2 Onychomycosis caused by candida and mold are not respond to griseofulvin treatment. Ketoconazole is effective in the treatment of candida onychomycosis but this agent may cause hepatic damage in idiosyncr ..................More
  Case Report
  Lymphocutaneous Nocardiosis
Yi-Hua Liao, Tsen-Fang Tsai, Chun-Hsiang Chang
Dermatol Sinica 15: 162-168, 1997

Two unusual cases of primary lymphocutaneous nocardiosis presenting as a primary inoculation ulcer and ascending nodular lymphangitis are herein reported. Fever and regional lymphadenopaty were also noted. One patient had a definite inoculation history by an abrasion wound that occurred three weeks prior to the development of the skin lesions. Histological examination of the subcutaneous nodules showed neutrophilic infiltration in the lower dermis and subcutaneous layer. Grams stain and modified ..................More
  Non-Clostridial Myositis
Ching-Hung Liu, Jau-Shiuh Chen, Chun-An Hsu
Dermatol Sinica 15: 169-172, 1997

Soft tissue infection is frequently misdiagnosed to be cellulitis in the early stage. We herein report a 58-year-old male patient with non-clostridial myositis, developing progressively extending painful lesions with gas accumulation over the buttocks and perineum. His disease was controlled only after extensive surgical excision. Soft tissue infection other than cellulitis composes of a heterogeneous group of diseases, sometimes with overlapping features. Fournier's gangrene occurs over the per ..................More
  Pemphigus Vulgaris Associated with Systemic Lupus Erythematosus
Chih-Chiu Wang, Wen-Jen Wang
Dermatol Sinica 15: 173-176, 1997

Pemphigus refers to a group of autoimmune blistering diseases of the skin and mucous membranes. Systemic lupus erythematosus (SLE) is a serious multisystem autoimmune disorder which frequently the skin and joints, and is characterized by high anti-nuclear antihbody (ANA) titres. Although both conditions are generally believed to be part of the autoimmune spectrum, each has distinctive clinical, histologic and immunopathologic characteristics. We describe herein, a 41-year-old female. Histology r ..................More
  Primary Mucinous Carcinoma of the Skin
Pi-Fen Lai, Jau-Shiuh Chen, Chung-Ren Tseng, Chun-An Hsu, Ching-Hung Liu
Dermatol Sinica 15: 177-180, 1997

Mucinous carcinoma is a rather rare primary neoplasm of the skin. We report a case of mucinous carcinoma of the skin in a 61-year-old otherwise healthy man, who presented with a bean-sized asubcutaneous nodule without overlying skin change on the left cheek. He had an excision at other hospital and received a wide excision again at our hospital because the tumor extended to the surgical margin. The pathology of the excised specimen showed a characteristic histopathologic feature of mucinous carc ..................More
  Juvenile Xanthogranuloma with Binocular Involvement
Tsun-Cheng Wang, Hsiu-Chin Chen, Lee-Jen Chen, Hsin-Yi Su
Dermatol Sinica 15: 181-185, 1997

A 7-month-old female baby presented with multiple cutaneous papules and haziness of the right eye. The result of skin biopsy was compatible with juvenile xanthogranuloma (JXG). The ophthalmologic examination revealed leucoma in the right eye, mile hyphema in the left eye, and bilateral glaucoma. Multiple cutaneous JXG with binocular involvement was diagnosed. Besides, the electro-encephalographic study showed abnormal waves and CT scan showed 2 calcified spots of unknown charaters in the frontal ..................More
  Cutaneous Rosai-Dorfman Disease: Report of a Case Treated with Isotretinoin
Ya-Huey Chuang, Heng-Leong Chan, Tseng-Tong Kuo
Dermatol Sinica 15: 186-193, 1997

We report a case of Rosai-Dorfman disease (RDD) confined to the skin. The patient was a 55-year-old woman, she presented with a history of gradual onset of multiple, nonternder, indurated plaques, and firm, subcutaneous nodules during 2 year-period. No fever, weight loss, or night sweating was experienced. Skin biopsy revealed a dense, nodular, dermal infiltrate composed of large histiocytes admixing with plasma cells, lymphocytes, and neutrophils and occasional emperipolesis. The diagnosis was ..................More
  Primary Cutaneous Rosai-Dorfman Disease
Chin-Lung Yang, Hsuan-Ying Huang, Ji-Chen Ho, Wei-Jen Chen
Dermatol Sinica 15: 194-199, 1997

Rosai-Dorfman disease (RDD)(Sinus histocytosis with massive lymphadenopathy) is a systemic proliferation of cells that resemble the sinus histiocytes of lymph nodes. Cutaneous lesions are usually associated with nodal or other extranodal location. We herein describe a female with RDD clinically limited to the skin. The patient presented with asymptomatic dermal nodules on the abdominal wall. Histologically, the lesion consisted of a proliferation of large histiocytes cytoplasmic positivity in th ..................More
  Lymphomatoid Granulomatosis
Yi-Quang Lin, Kao-Chia Yang
Dermatol Sinica 15: 200-206, 1997

A 20-year-old male patient presented with several erythematous papulees and plaques, between 0.5 and 1.5cm in size, sepontaneously arising on the trunk and extremities during the past 3 years. Some of them resulted in ulcers. They occurred off and some healed spontaneously with scars. Skin histopathology revealed many angiocentric and angiodestrucive polymorphous infiltrates in the dermis consisting of small to medium-sized lymphocytes and hisiocytes. Many lymphocytes were atypical. They invaded ..................More
  Cutaneous Metastases from Hepatoma
Shih-Tzu Tseng, Ming-Yeu Lee, Ho-Hsing Chang
Dermatol Sinica 15: 207-210, 1997

A 51 year-old male presented with a papule over forehead noted 10 days ago. Biopsy of the lesion revealed neoplastic cells arranged in trabecular pattern in dermis. Cutaneous metastases from heatoma was diagnosed. Hepatoma with skin metastases were rarely reported in the literature and they accounted for less than 1% of total cutaneous metastases, even rarer to be the first sign of hepatoma. We report this case for clinical dermatological interest. ..................More
  Tuberculosis Verrucosa Cutis Associated with Cutaneous Ulcer
Han-Chieh Lee, Chung-Hsing Chang, Hsin-Su Yu
Dermatol Sinica 15: 211-215, 1997

A 39-year-old male patient presented with an exacerbated ulceration on his left intergluteal to inguinal area for two months. During his childhood, the lesion was a small nodule on his left buttock. With age, it slowly enlarged into an irregular verrucous plaque with itching sensation and occasional erosion due to over scratch. Wound culture yielded Pseudomonas aeruginosa. Histopathological examination revealed a granulomatous infla-mmation with caseous necrosis and multiple Langhan's giant cell ..................More
  Scrub Typhus
Chieh-Shan Wu, Chung-Hsing Chang, Gwo-Shing Chen, Hsin-Su Yu
Dermatol Sinica 15: 216-221, 1997

Scrub typhus, also named Tsutsugamushi disease, is an acute febrile infectous disease caused by Rickettsia tsutsugamushi and mediated by mite. It was prevailing in south and north east Asia countries, Indonesia, and Pacific islands including Taiwan and Pescadores Islands. Since 1970, it has been rarely found in Taiwan area with exceptions of the east coast and neighboring islands. We herein report a 65-year-old female from the Pescadores Island who suffered from intractable prolonged fever & cgu ..................More
  Prurigo Pigmentosa
Wen-Jang Liaw, Han-Nan Liu, Run-Yee Lin, The-Lu Chu
Dermatol Sinica 15: 222-225, 1997

A 23-year-old female visited our OPD due to itchy reddish lesions and gross reticular pigmentation over the back for 2 years. According to the patient, the reddish eruptions disappeared leaving reticulate pigmentation without any treatment. However, new episode developed in the following, summer. Physical examination revealed multiple erythematous papules and brownish reticular, mottled pigmentaion symmetrically distributed on her back. Histologically, it is characterized by lichenoid infiltrati ..................More
  Inverse Psoriasis
Chao-Shyang Chang, Chang-Lin Chen, Chu-Kwan Wong
Dermatol Sinica 15: 226-230, 1997

Inverse psoriasis is an uncommon variant of psoriasis. Because the distribution and characteristics of inverse psoriasis are quite different from those of psoriasis vulgaris, it is difficult to make a correct diagnosis and treatment. We herein report a case of 26-year-old female patient who suffered from mildly itchy, scaly, erythematous plaques with erosion and fissures over the umbilicus, perimeum, intergluteal folds, bilateral axillae, and retroauricular region for half an year. Besides, grou ..................More
  The Experience of Acute Hepatic Failure During Steroid Treatment
Wen-Ling Huang, Hsu-Po Yeh, Ruey-Yi Lin, Herng-Ming Leu
Dermatol Sinica 15: 231-235, 1997

A 81-year-old asymptomatic hepatitis B carrier presentd with lower limb itching skin rashes for 2 months. Bullous pemphigoid was diagnosed by histopathology and immunofluorescent method. The skin lesion improved during steroid treatment. However, fatal acute hepatic failure developed during tapering of steroid. We experienced that immunosuppressive treatment in patient with viral hepatitis could be risky. It may be related to increased viral replication followed by immunosuppressive treatment wh ..................More
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