Back issues No.4 - 1997  
  Original Study
  Comparison of positive rate in detecting Anti-Golgi Antibodies by indirect immunofluorescence using Hep-2 cells and IMR-33 cells as substrate
Hong-Shang Hong, Yea-Huey Chuang, Shao-Yei Liu, Jwo Farn Chiou
Dermatol Sinica 15: 236-241, 1997

In order to perform the related experiments concerning the Anti-Golgi Antibodies (AGA) or Golgi antigens, the way to detect and get AGA-positive sera is the most important thing. Previous authors used the animal tissue section as the substrate of the indirect immunofluorescence (IIF) to detect AGA, but the result is not satisfactory. To use the Hep-2 cells as substrate in IIF is quite popular now. There were authors used IMR-33 as substrate in indirect immunofluorescence and speculated the AGA w ..................More
  Double Blind Clinical Trial of 0.05% Isotretinoin gel and 0.05% Tretinoin cream for Treatment of Acne
Chen-Nai Wang, Heng-Leong Chan
Dermatol Sinica 15: 242-248, 1997

This was a randomised, double-blind, parallel-group study to compare the efficacy and tolerance of 0.05% isotretinoin gel (ISOTREX) with 0.05% tretinoin cream (Retin-A) in the treatment of acne. A total of 60 patients (10 males and 50 females), aged from 15 to 30 years, were entered into the 3 month study that was carried out from September 1994 to January 1995. Complete data from 59 patients (30 patients from the Retin-A group and 29 from the ISOTREX group) were available for evaluation. Both t ..................More
  Hyperpigmentation with Confetti Appearance-The Sequelae of Facial Application with Piper Betle Leaf: A Clinical Survey of 137 Patients
Lih-Jen Yang, Dong-Yu Chen, Heng-Leong Chan
Dermatol Sinica 15: 249-255, 1997

Backgroud: One hundred and thirty-seven patients presented with severe hyperpigmentation and confetti macules on the face after an outbreak of fantastic use of Piper betle leaf for clearing of pigmented spots. Objective: To investigate the etiologies, objectives, effects and sequelae of these users. To treat and follow up these pigmented disorders. Method: The detailed histories of these users were recorded. The therapies consisted of 4% hydroquinone, 0.05% clobetasone butyrate or 0.1% mometason ..................More
  Case Report
  CREST SYNDROME WITH Anticentromere Antibody combines with PBC:A Rare Case with Family Predisposition to Autoimmune Disorders
Hong-Shang Hong, Jwo-Farn Chiou
Dermatol Sinica 15: 256-261, 1997

A 53-year-old nonalcholic female was diagnosed as CREST syndrome (calcinosis cutis, Rayuaud’s phenomenon, esophageal dysfuntion, sclerodactyly, telangiectasia) combined with primary biliary cirrhosis (PBC). She was also sensitive to penicillin and sun light. Autoantibody tests showed antimitochondrial antibody (AMA), anticentromere antibdy (ACA) in her serum. Family history revealed her mother had chronic thyroiditis, elder sister had rheumatoid arthritis, and her younger sister died due to no ..................More
  Annular Erythema Associated with Sjogren's Syndrome -A Case Report Review of the Literature-
Hsiou-Hsin Tsai, Ding-Da Lee, Chu-Kwan Wong
Dermatol Sinica 15: 262-267, 1997

Patients with Siogren’s syndrome were recently were recently reported to frequently develop annular erthematous lesions that are clinically and histopathologically distinct from subacute cutaneous lupus erythematosus (SCLE). Most of the cases are from the Asian areas, especially from Japan. We present a 41-year-old Chinese female patient of recurrent annular erythema with the same clinical, serologic and histopathologic features as those previously reported. ..................More
  Diffuse Neonatal Hemangiomatosis-A Case Report-
Chia-Chun Kao, Chieh-Jen Huang, I-Chung Hung
Dermatol Sinica 15: 268-274, 1997

We report a case of a rare disease-diffuse neonatal hemangiomatosis (DNH). This patient was sent to our department due to some cherry-red skin lesions developed soon after birth. Skin biopsy was done and the histopathological examination revealed if benign capillary hemangioma. At about 2 weeks of age, he was noted of poor feeding, tarry stool passing, and pale appearance and admitted to ward. Under the examinations of endoscopy, laparotomy, nuclear medicine, magnetic resonance imaging (MRI), an ..................More
  Lymphangiectasia-Report of One Case and Review of the Literature-
Mei-Hsin Chang, Guang-Hsiang Shiao, Chung-Ren Tseng
Dermatol Sinica 15: 275-279, 1997

Lymphangiectasia(acquired lymphangioma)is a rare cutaneous condition due to lypmhatic obstruction of various processes. It is clinically and histologically indistinguishable from lymphangioma circumscriptum. Detailed istory and identifying the cause are essential for a definite diagnosis. We describe a 64-year-old woman with vulvar lymphangiectasia which was secondary to treatment of cervical carcinoma. A review of literature is also made. ..................More
  Granuloma Annulare Occurring in Herpes Zoster Scre-A Case Report-
Shu-Ching Hu, Chung-Ren Tseng, Li-Fang Wang
Dermatol Sinica 15: 280-284, 1997

One case of granuloma annulare in herpes zoster scar, was first described by Guill and Goette in 1978. Here, we report a similar case. A 61-year-old man suffered from herpes zoster over the right lower back 5 months ago. About one month after vesicular lesions resolved, many erythematous papules appeared at the site of the scar relating to herpes zoster with itching and painful sensation. Microscopically, there are necrobiosis with the accumulation of lymphocytes, histiocytes, and fibroblasts in ..................More
  Chronic Cutaneous Infection Caused by Mycobacterium gordonae -A Case Report and Review of Literature-
Pi-Fen Lai, Wei-Cheng Lu, Tsen-Fang Tsai
Dermatol Sinica 15: 285-289, 1997

Mycobacterium gordonae was considered one of the least pathogenic bacillus of mycobacterium other than tuberculosis(MOTT), but there are now well-documented reports of infection varying from localized cutaneous infection to disseminated life-threatening diseases. We report a 35-year-old healthy man with chronic cutaneous infection caused by M. gordonae. The clinical feature was one erythematous nodule on the dorsum of right hand for more than six months. The histopathologic picture showed ma ..................More
  Purely Cutaneous Rosai-Dorfman Disease Case Report and Review of the Literature
Yen-Liang Chem, Tsuo-Wu Lin, Shiou-Feng Huang, Tsen-Fang Tsai
Dermatol Sinica 15: 290-295, 1997

Rosai-Dorfman disease is an uncommon disease affecting individuals of either sex and of all ages. Cutaneous lesions of Rosai-Dorfman disease are usually associated with nodal or other extranodal localization. Purely cutaneous Rosai-Dorfman disease is rare. We present a 33-year-old woman with Rosai-Dorfman disease clinically limited to the skin. The patient presented with a 14x10 cm dark brownish, irregularly shaped plaque with many subcutaneous nodules on her right thigh. Histology showed nodula ..................More
  Pigmented spindle cell nevus of Reed-A Case Report and Review of Literature-
Chih-Chiu Wang, Wen-Jen Wang, William Lin Ho
Dermatol Sinica 15: 296-300, 1997

The pigmented spindle cell nevus(PSCN)was only first properly described in 1975 by Reed et al1 in an excellent review of melanocytic tumors, as a distinct variant of spidle and epitheloid(Spitz)nevus. It is an uncommon lesion with a distinctive clinical presentation --- a well circumscribed deeply pigmented papule usually of recent onset, frequently located on the proximal extremities(thighs)of young adults. It differs from the usual Spitz tumor in its capacity to produce melanin and ..................More
  Xanthoma Disseminatum-A Case Report and Literature Review
Tzu-Cheng Huang, Yu-Chang Chan, Yuh-Chiau Chiang, Kwan-Chin Tseng
Dermatol Sinica 15: 301-305, 1997

Xanthoma disseminatum(XD)is a rare normolipemic xanthoma nowadays classified as a benign non-Langerhans cell histiocytosis. We report a 15-year-old girl with orange-brown papules on her face, axillae and neck, where some coalesced into plaques. A biopsy from the axillary region revealed dense infiltration of foamy cells, histiocytes, lymphocytes and few Touton giant cells in the dermis. Based on the clinical and pathological findings, a diagnosis of xanthoma disseminatum was made. ..................More
  Cutis Marmorata Telangiectatica Congenita with Multiple Congenital Anomalies-A Case Report-
Jeng-Jer Chen, Hsiu-Chin Chen, Hsin-Yi Su
Dermatol Sinica 15: 306-311, 1997

A male neonate had widespread violet-red, reticulated network over the entire body surface and phlebectasia on the scalp and abdomen. There were also several superficial ulcers on the scalp. The patient suffered from respiratory distress soon after birth. The chest x-ray showed bluntness of the costophrenic angle of the right lung caused by pleural effusion. The heart echo showed patent ductus arteriosus and atrial septal defect. Ophthalmic examination revealed bilateral congenital glaucoma and ..................More
  Neonatal Lupus Erythematosus-A Case Report-
Chao-Shyang Chang, Chang-Lin Chen, Chu-Kwan Wong
Dermatol Sinica 15: 312-316, 1997

Neonatal lupus erythematosus is a disease of infancy characterized by subacute cutaneous lupus erythematosus-like lesions, congenital heart block, or both. It is associated with transplacental passage of maternal autoantibodies, predominantly the anti-Ro(SSA)antibody. The cutaneous lesions usually resolve at the age of 6 months. The congenital heart block is usually permantent and of third digree. A 45-day-old female infant had multiple annular, scaly, erthematous plaques over the face, trun ..................More
  Disseminated Penicillium marneffei infection with cutaneous lesion in an HIV infected Taiwanese patient-A Case Report-
His-Lun Su, Ming-Tzen Liu, Chu-Kwan Wong
Dermatol Sinica 15: 317-321, 1997

We report a 44-year-old male with disseminated Penicillium marneffei infection who had scattered pea-sized erythematous infiltrated papules, pustules with erosive and crusted surfaces. He also had other systemic symptoms and signs including cough,hemoptysis,intermittent fever, and body weight loss. Histopathology of skin biopsy on left xheek showed numerous yeast-like cells within the histiocytes as well as in the extracellular location. Fungal culture from tissue of skin biopsy, pus blood, sput ..................More
  Eruptive Vellus Hair Cyst and Steatocytoma Multiplex, Variants of One Entity?-A Case Report and Literature Review-
Hsiou-Hsin Tsai, Chang-Lin Chen, Chu-Kwan Wong
Dermatol Sinica 15: 322-325, 1997

Eruptive vellus hair cyst(EVHC), a condition first described in 1997, is similar to steatocystoma multiplex(SM)clinically. Both diseases are characterized by the formation of multiple cutaneous cysts and having inherited transmission with variable penetration. They are also similar in terms of age of onset, location and appearance of the lesions. They can be differentiated only by histopathology. However, several recently reported cases suggested a close relationship between EVHC and SM. ..................More
  Cutaneous Cliated Cyst-A case report-
Yu-Fu Chen, Shu-Ling Hu, Chih-Ming Hung
Dermatol Sinica 15: 326-328, 1997

Cutaneous ciliated cysts almost exclusively occur in women and have been widely regarded as Mullerian heterotopias. The cysts represent a rare completely benign entity lined by ciliated columnar cells. We report a case of this lesion occurring in the buttock of a 20-year-old woman and review the literature. ..................More
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