Back issues No.2 - 1999  
  Original Study
  Building a Multi-purpose Dermatology Resource on the Internet
Yu-Chuan Li, Hsien-Hung Lai, Chan-Shin Chiu, Chung-Hong Hu
Dermatol Sinica 17: 94-103, 1999

This paper describes a major dermatological multimedia resource in Taiwan, which was named Advanced Dermatology Education Server (ADES). The ADES was built under the infrastructure of the Internet that can be accessed from all over the world through any World-Wide Web browsers. The ADES distinguishes itself with other medical education modalities in that it is ubiquitous, interactive, concurrent, up-to-date and freely searchable. The ADES features three major segments: I. Skin problem Q & A, II ..................More
  Case Report
  The Ocular Complications of Herpes Zoster Ophthalmicus-A Study of Hutchinson's Sign-
Chia-Lin Liu, J. Yu-Yun Lee, M. Ming-Long Hsu, Sheau-Chiou Chao, Tak-Wah Wong, Hamm-Ming Sheu
Dermatol Sinica 17: 104-111, 1999

In case of herpes zoster affecting the trigeminal nerve, the close relationship between the in volvement of the nasociliary branch and ocular complications is well known. The most striking clinical feature is the presence of a herpetic rash on the tip of the nose, the so-called Hutchinson' s sign. This study assessed the reliability of Hutchinson' s sign in the prediction of ocular complications. A total of 93 patients hospitalized for herpes zoster of the ophthalmic distribution of cranial n ..................More
  Scrub Typhus Complicated with Acute Respiratory Distress Syndrome
Ing-Ruey Chang, Yu-Hung Wu, Chang-Yi Lin, Hsin-Yi Su
Dermatol Sinica 17: 112-118, 1999

A 28-year-old aboriginal female complained persisting headache, fever and skin eruption. There were scattered erythematous papulovesicles on the face, trunk and extremities. Chest X-ray revealed bronchiolitic change. She was admitted as chickenpox with bronchitis, and received antiviral therapy. However, acute respiratory distress status developed and an eschar was found on the left lower quadrant of abdomen. Serum indirect immunofluorescence test showed Rickettsia tsutsugamushi Ab IgG+A+M≧1:6 ..................More
  Borderline Lepromatous Leprosy
Ya-Ju Hsieh, Hsin-Yi Su, Hsiu-Chin Chen
Dermatol Sinica 17: 119-123, 1999

A 65-year-old male presented with erythematous papuloplaques on bilateral forearms initially. The skin lesions spread to the face, trunk and distal four extremities in subsequent four months. The result of histological examination revealed heavy dermal infiltration of foam cells and lymphocytes, and many acid fast stain positive leprosy bacilli. Lepromin test was negative, and bacteria index of slit skin smear was 4.2. These indicated a case of borderline lepromatous leprosy.We started standard ..................More
  Pyoderma Gangrenosum in Childhood-Report of a Case and Review of the Literature-
Chan-Ho Lai, I-Hsin Shih, Heng-Leong Chan
Dermatol Sinica 17: 124-131, 1999

Pyoderma gangrenosum (PG) is an uncommon ulcerative skin disorder that occurs in all age groups. It rarely occurs in children. We report a case of a 3-year-8-month-old boy with PG on his right leg. No underlying disease was found. He was treated with intravenous steroid and no relapse occurred during 20-month follow-up. We reviewed the childhood cases (≦16 years of age) reported in the literature for the clinical features, associated disorders, and therapy. There were 62 patients in total, inc ..................More
  Autotransplantation in Vitiligo-A Case Successfully Treated with Epidermal Grafts and Cultured Autologous Melanocytes-
Yu-Fu Chen, Pey-Yuh Yang, Chih-Ming Hung, Ming-Ho Huang, Dan-Ning Hu
Dermatol Sinica 17: 132-139, 1999

A 12- year-old girl with stable segmental type vitiligo received two different methods of pigment cell transplantation, including epidermal graft by suction blister and application of suspensions of cultured autologous melanocytes. The repigmented portion of total treated area amounted to > 95%. At follow-up after 8 months, the repigmented areas remained unchanged. The result obtained indicates that the procedure combining epidermal graft with the application of suspensions of autologous cultur ..................More
  Hand-Schuller-Christian Disease
Shiuh-Fung Horng, Chih-Chou Chen, Jui-Lung Shen, An-Hang Yang
Dermatol Sinica 17: 140-147, 1999

A 18-month-old boy suffered from multiple erythematous scaling papuloplaques with some serous crusts, excoriation markings and few pustules on his scalp soon after birth. He had been treated as seborrheic dermatitis, but poor response to topical steroid was noted. Exophthalmos and skin lesions got worse in recent two months. Light microscopic examination of the skin specimen revealed extensive histiocyte infiltration on dermo-epidermal junction and exocytosis of these cells. S-100 protein stain ..................More
  Syringocystadenoma Papilliferum with Unusual Clinical Features
Li-Chen Cheng, Yuan-Li Liao, Yuh-Chiau Chiang, Ren-Fong Lee
Dermatol Sinica 17: 148-152, 1999

Syringocystadenoma papilliferum is an uncommon adnexal adenoma mostly located on the head and neck. We describe a 19-year-old male patient who had five erythematous, aggregated oval papules with punctate surface on the abdomen. They varied in size from 8 mm to 1.6 cm and were firm in consistency. The diagnosis of syringocystadenoma papilliferum was established based on the typical histopathologic features. ..................More
  Systemic Lupus Erythematosus Associated with Calcinosis Cutis-A Case Report and Review of the Literature-
Jeng-Yi Liu, His-Ching Wang, Chin-Chou Chen, Jui-Lung Shen
Dermatol Sinica 17: 153-159, 1999

Calcinosis cutis is commonly associated with several connective tissue diseases, but is rare in systemic lupus erythematosus (SLE). We report a case of calcinosis cutis in a 31-year-old woman with a 7-year history of SLE. Multiple skin-colored, hard, asymptomatic subcutaneous nodules developed gradually over both her lower legs 6 years after the diagnosis of SLE. A skin biopsy revealed calcinosis cutis. Subcutaneous calcifications were found over her lower legs by radiological studies. The serum ..................More
  Disseminated Superficial Porokeratosis with Amyloid Deposition
Ching-Ya Wang, Hsu-Po Yeh, Chun-Hsian Chang
Dermatol Sinica 17: 160-164, 1999

We report a case of disseminated superficial porokeratosis (DSP) with amyloid deposition in a 72-year-old male patient. He had had many annular keratotic macules on the trunk and upper extremities for more than 20 years. Pruritus of the lesions was noted in the past 2 months. No evidence of actinic induction was noted. Histopathology showed cornoid lamellae and hypogranulosis in the hyperkeratotic area. Amyloid deposition was seen in the dermal papillae not only beneath the cornoid lamellae but ..................More
  Basaloid Follicular Hamartoma
Kuo-Dong Liao, Ming-Tuo Chuan, Hon-Ru Yu, Yeh Peng
Dermatol Sinica 17: 165-171, 1999

Basaloid follicular hamartoma is a rare disease, which is characterized by a distinct histopathologic pattern and in a wide range of clinical presentations. We report a 29-year-old female with linear brownish papules and macules over the right thigh, lower leg and foot which developed several months after birth. Deformity of the right leg was also noted during puberty. Histopathologic examination of the skin lesions revealed typical findings of basaloid follicular hamartoma. This is the firs ..................More
  Neurofibromatosis Type II
Chu-Hui Tu, Hsien-Ching Chiu
Dermatol Sinica 17: 172-177, 1999

An 11-year-old boy presented with a newly developed, well-defined, palpable but invisible, cord-like subcutaneous nodule over the right cheek. He also had exhibited totally 12 variously sized, flesh to light brownish, semi-firm papules and nodules over the scalp, face, trunk and extremities since he was 2 years old. The physical examination failed to reveal any cafe-au-lait spot, axillary freckling, Lisch nodule or posterior subcapsular cataract. He never experienced hearing loss or tinnitus in ..................More
  Primary Vibrio Vulnificus Septicemia
Tzong-Len Sheu, Shei-Tai Liu, Ji-Chen Ho
Dermatol Sinica 17: 178-183, 1999

We report a case of primary Vibrio vulnificus septicemia in a 53-year-old male patient with history of alcoholic liver cirrhosis, who had shortly consumed raw oyster. The initial presentation was fever, chill, and urticarial plaques and purpuric patches on the trunk and both thighs. The course rapidly progressed to septic shock and death in 24 hours. Because of the popularity of consuming raw seafood and the high prevalence of chronic liver disease in Taiwan, clinicians should be alert to this p ..................More
  Generalized Hair Follicle Hamartoma Associated with Systemic Lupus Erythematosus
Hung-Wen Kuo, Cheng-Hung Lin, Ji-Chen Ho, Shun-Chen Huang
Dermatol Sinica 17: 184-190, 1999

A 60-year-old Taiwanese women with a 7-year history of systemic lupus erythematosus presented with infiltrative papules and plaques on her face and ears for 6 months, and progressive loss of the scalp, eyebrow, axillary, and pubic hairs and lower eyelashes for 6 years. Histologic sections taken from the right nasolabial fold and right ear demonstrated anastomosing cords and islands of basaloid cells in the dermis embedded in a cellular stroma, and some hair bulb-like structures were noted in the ..................More
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