Back issues No.1 - 2000  
  Original Study
  Allergic Contact Dermatitis to Povidone-iodine
I-Wen Su, Chee-Ching Sun
Dermatol Sinica 18: 1-5, 2000

Povidone-iodine (PVP-I) is a widely used antiseptic, and report of allergic contact dermatitis has been rare. We retrospectively studied the cases patch-tested with PVP-I in National Taiwan University Hospital in the past 21 years. Totally 22 patients were patch-tested, among which 8 patients gave positive reactions. Three patients were further patch-tested with iodine tincture and all gave positive reactions. We therefore suggest that patients with known history of allergy to iodine should ..................More
  Case Report
  Primary Cutaneous Diffuse Large B Cell Lymphoma
Kuan-Cheng Hung, Kao-Chia Yang, Huei-Mei Chang
Dermatol Sinica 18: 6-13, 2000

Primary cutaneous B-cell lymphoma (PCBCL) is an extranodal non-Hodgkin's lymphoma that primarily appears in the skin without detectable extracutaneous location. We report a 60-year-old man presented with multiple asymptomatic, indurated, erythematous to violaceous plaques on his upper back for more than two years. The histopathological examination showed a dense, patchy dermal infiltrate composed mainly of atypical lymphoid cells with large vesicular nuclei and occasional prominent nucleoli. The ..................More
  Clear Cell Syringoma
Chih-Tsung Lin, Ming-Tzen Liu, Chang-Lin Chen, Chu-Kwan Won
Dermatol Sinica 18: 14-17, 2000

Clear cell syringoma is a rare variant of syringoma1. We report a 58-year-old woman who has had numerous asymptomatic, 1 to 3 mm, skin-colored papules over the bilateral periorbital areas since puberty. The histopathological examination showed several small lobules of clear cells with centrally located eccrine ducts in the upper dermis. Her mother and daughter had the same lesions since puberty. The patient was diagnosed as having diabetes mellitus in 1995 and was treated with oral anti-hypergly ..................More
  Muir-Torre syndrome
Yu-Ben Pong, Ding-Dar Lee, Chang-Lin Chen, Wen-Jen Wang, Chu-Kwan Wong
Dermatol Sinica 18: 18-22, 2000

The Muir-Torre syndrome is an unusual genodermatosis combined with malignant potential. It is a hereditary autosomal dominant disease with a variable degree of penetrance and is defined by the presence of at least a single sebaceous gland tumor (adenoma, epithelioma, or carcinoma) and a minimum of one visceral malignancy. A 68 year-old man was diagnosed as adenocarcinoma of the rectum with metastasis to the lung and liver 2 years ago. He visited our clinic with a lesion of sebaceous adenoma on h ..................More
  Myxoid Neurothekeoma
Hsin-Chi Chen, Jeng-Jer Chen, Hsiu-Chin Chen, Hsin-Yi Su
Dermatol Sinica 18: 23-27, 2000

A 29-year-old male presented with a slightly tender, skin-colored, soft nodule measuring 1.0 cm in diameter on his right post-auricular area for about six months. He received total excision of the lesion at our OPD. Both histopathological and immunohistochemical examinations revealed characteristic changes of myxoid neurothekeoma (nerve sheath myxoma). We report this uncommon tumor and review the literature briefly. ..................More
  Clear Cell Acanthoma-Report of Two Cases-
Kwan-Jou Chu, Fon-Yi Sung, Kai-Yam Ng, Kou-Chang Chou
Dermatol Sinica 18: 28-31, 2000

We report two cases of clear cell acanthoma. One case presented with a dome-shaped pinkish nodule with fine scales on the gluteal area, and the other with brownish nodule measured 1cm in diameter on the back. Total excisions were performed and the characteristic pathologic features showed clear cell acanthoma. Origin of the clear cell is also reviewed. ..................More
  Harlequin Ichthyosis-Report of A Case Treated With Acitretin-
Teng-Fu Hsu, Yih-Shun Chen, Kao-Chia Yang
Dermatol Sinica 18: 32-36, 2000

Harlequin ichthyosis is a rare inherited skin disorder with unknown pathogenesis and is considered to be a severe form of congenital ichthyosis and is usually fatal. We report a case of a male infant with generalized hyperkeratosis, whose clinical features were striking and characteristic for harlequin ichthyosis. Acitretin was applied from the day 3. He has survived for more than 5 months until now. We will follow-up his condition. ..................More
  Acrokeratosis verruciformis of Hopf
Chien-Ping Chiang, Run-Yu Lin, Chin-Yaw Eric Wang, Wei-Ming Wang
Dermatol Sinica 18: 37-42, 2000

Acrokeratosis verruciformis of Hopf is a rare genodermatosis transmitted as an autosomal dominant trait. We herein report a 19-year-old male patient who presented with multiple discrete warty papules on his dorsal hands and feet since early childhood. Besides, he also had quite a few small hypopigmented papules scattered throughout his anterior trunk and some hyperpigmetned papules located on a patch over his left neck. Multiple skin biopsies with serial sections were performed. Histopathology s ..................More
  Rhabdomyomatous Mesenchymal Hamartoma
Chao-Hong Liu, Meng-Tse Wu, Tze-Yi Lin
Dermatol Sinica 18: 43-46, 2000

We present the case of an 8-year-old girl who presented with a skin-colored nodule on the chin since birth. Physical examination was otherwise unremarkable. Histologically, the lesion showed haphazardly arranged or vertically orientated, mature skeletal muscle bundles in the lower dermis and subcutis. Based on these clinical and histologic findings, a diagnosis of rhabdomyomatous mesenchymal hamartoma was made. To our knowledge, this is the first reported case of this tumor in Taiwan. ..................More
  Paraneoplastic Pemphigus
Po-Hung Chen, Gwo-Shing Chen, Roger Chin-Che Hsu, Hsin-Su Yu
Dermatol Sinica 18: 47-53, 2000

Paraneoplastic pemphigus is a rare neoplasia-associated autoimmune bullous disease. Here we report a case of this unusual disorder with erosions over oral mucosa, and multiple erosive erythematous plaques with elevated margins over the extremities and trunk. Initially, Stevens-Johnson syndrome was impressed. However, the histopathology showed a supra-basal cleft and a lot of acantholytic keratinocytes within the cleft. Direct immunofluorescence revealed depositions of IgG and C3 in the intercell ..................More
  Acquired Circumscribed Hypertrichosis
Liang-Yuan Wu, Yu-Fu Chen, Chih-Ming Hung
Dermatol Sinica 18: 54-58, 2000

A 22-year-old mentally defective female presented with several localized long hairs on the superior area of the anterior side of her neck for several months. Histopathological examination showed a normal appearance of hair follicles. The clinicopathological features are compatible with acquired circumscribed hypertrichosis, and the possible etiologic factor is repeated irritation. ..................More
  Pustular Jarisch-Herxheimer Reaction in a Patient of Secondary Syphilis Treated with Penicillin
Hui-Hsien Chiu, Heng-Leong Chan, Tseng-Tong Kuo
Dermatol Sinica 18: 59-64, 2000

Jarisch-Herxheimer reaction is a self-limited febrile reaction with exacerbation of lesions of infective origin after antimicrobial therapy and is classically observed in the treatment of early syphilis with penicillin. We present a case of the rarely described pustular variant of Jarisch-Herxheimer reaction in a patient of secondary syphilis treated with penicillin and review the possible pathogenetic mechanism. ..................More
  Scleromyxedema: Satisfying Response to Etretinate -Report of one case-
Chen-Chin Chung, Hsu-Jung Hsieh, Tze-Yi Lin
Dermatol Sinica 18: 65-73, 2000

A 28-year-old male patient presented with multiple flesh-colored to erythematous nodules over the forehead, back, chest, scapula, elbows, both hands and lower legs, and numerous small uniform-sized papules in linear pattern on indurated skin over scalp, retroauricular area, nape of the neck, and axillae for about one year. Histopathology of the dermal nodule over the elbow and the plaque over the nape of the neck showed mucin deposition in upper dermis which was positive with alcian blue at pH 2 ..................More
  Tuberculosis Cutis Orificialis
Pei-Yu Lo, Nai-Jen Hsu, Tien-Yu Tzung, Tsu-Chyang Chen
Dermatol Sinica 18: 74-79, 2000

Tuberculosis cutis orificialis (TCO) is a rare manifestation of cutaneous tuberculosis that occurs in mucous membranes and skin adjacent to natural orifices due to autoinoculation of bacilli from advanced visceral tuberculosis. We report a 71-year-old male who suffered from inflammatory nodules over right side of the gluteal region for one year. The skin eruptions soon became scattered or confluent perianal ulcers. Histopathology of a biopsy specimen showed several granulomas with caseous necros ..................More
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