Back issues No.3 - 2000  
  Original Study
  Epidemiology and Clinical Analysis of Paederus Dermatitis in Taitung, Taiwan
Yuan-Hsin Lo, Yu-Hung Wu, Hsin-Yi Su
Dermatol Sinica 18: 177-184, 2000

Paederus dermatitis is an irritant contact dermatitis caused by body fluid of Paederus. Due to its common occurrence and overlapping features with other dermatoses, we conducted a survey of its epidemiology and clinical appearance. The ages of the total 63 patients(female 37, male 26) range from 3 months to 72 years, with a mean of 28.2 years. The number of the patients increased gradually from May and reached peak from June through August. The number declined sharply thereafter, and only sporad ..................More
  Case Report
  Blister Fluid for the Diagnosis of Bullous Pemphigoid: Experience in 3 Cases
Ya-Yi Chang, Roger Chin-Che Hsu, Gwo-Shin Chen, Yuh-Lan Suen, Hsin-Su Yu
Dermatol Sinica 18: 185-190, 2000

Bullous pemphigoid (BP) and other subepidermal autoimmune bullous diseases such as cicatricial pemphigoid, pemphigoid gestationis, linear IgA bullous dermatosis and epidermolysis bullosa acquisita are characterized by the presence of circulating and/or in situ deposition of autoantibodies to self-antigens in the cutaneous basement membrane zone. Direct and indirect immunofluorescent studies are routine diagnostic tests to detect autoantibodies in these diseases. In this study, we compared the ti ..................More
  Classic Kaposi' s Sarcoma with Oral Involvement - A case report -
Bo-Jing Chen, Yun-Ting Chang, Wen-Jeng Wang, Chu-Kwan Wong
Dermatol Sinica 18: 191-196, 2000

There are four subtypes of Kaposi' s sarcoma including classic, African, AIDS-associated and immune suppression. Oral lesions are usually seen in patients with AIDS-associated Kaposi' s sarcoma while the oral involvement in patients with classic Kaposi' s sarcoma is extremely rare. We report a 76-year-old married male with multiple violaceous nodules on his lower limbs for 7 years. An oral lesion developed seven years after onset of the skin lesions. Histopathological examination on the skin and ..................More
  Pemphigus Vegetans- A case report -
Dong-Jia Tsai, Tien-Yi Tzung, Tsu-Chyang Chen
Dermatol Sinica 18: 197-203, 2000

A 71-year-old male had generalized bullous lesions and oral ulcers 15 years ago. Pemphigus vulgaris was confirmed by skin biopsy and immunofluorescence study. He received treatment with oral prednisolone and azathioprine and had good response. In May 1998, an erosive, verrucous, vegetative plaque was noted over vermilion border of the lip and left side of perineum. Histopathologic examination showed suprabasal acantholysis and intraepidermal microabscesses containing numerous eosinophils. Direc ..................More
  Cutaneous Sparganosis- A case report -
Chen-Chin Chung, Bor-Jeng Tsai, Tze-Yi Lin, Hsiu-Maan Kuo
Dermatol Sinica 18: 204-210, 2000

Sparganosis is an infection caused by plerocercoid larvae of Diphyllobothriidae tapeworms. There have been 19 cases reported in Taiwan since 1922. Fifteen cases were caused by Sparganum mansoni, and four by Sparganum proliferum. We present cutaneous sparganosis in a 64-year-old woman, who noted a painful ulcerated, soft nodule on her right leg for three months after touring a beach in Thailand. Several thread-like worms, which measured from 4 mm to 5 cm, were squeezed from the ulcerated nodule d ..................More
  Pyoderma Gangrenosum Associated with Myelodysplastic Syndrome
Tsu-Man Chiu, Kao-Chia Yang, Cheng-Shyong Chang
Dermatol Sinica 18: 211-218, 2000

Pyoderma gangrenosum(PG)is an uncommon, ulcerative, cutaneous disorder with distinctive clinical characteristics. We report a 62-year-old woman who had had extensive painful ulcers over bilateral calves for 11 months when she was admitted to our hospital. Although she had been treated as having infectious ulcers(including surgical excision)at other hospitals, but the ulcers continued to aggravate. According to the findings from the skin biopsy, the microbial culture results, the characteristics ..................More
  Embryonal Rhabdomyosarcoma with Skin Invasion Mimicking a Perianal Abscess
Chia-Yi Yang, I-Hsin Shih, Chun-Min Wang, Hang-Leong Chan
Dermatol Sinica 18: 219-222, 2000

A 9-month-old girl was found to have an erythematous lesion on her buttock after an episode of watery diarrhea. Perianal abscess was suspected initially. The girl was then treated with parenteral antibiotics the response of which, however, was poor. Further histological examination of the lesion revealed that the lesion was due to a rhabdomyosarcoma. We report the case and review the literature. ..................More
  Pure Epithelioid Spitz Nevus with Easily Bleeding Character A case report & literature review-
Cheng-Lun Hsiao, Su-Ying Wen
Dermatol Sinica 18: 223-228, 2000

Spitz nevus is a rare benign skin tumor. Histologically it may be classified as spindle cell nevus and mixed cell type of spindle and epithelioid cell. Pure epithelioid Spitz nevus is rare. A 24-year-old male had a 0.8×0.8×0.5cm smooth-surfaced, elastic, red-brownish, dome-shaped nodule over the lateral aspect of the right thigh and suffered from one episode of massive bleeding. Clinically it resembled a pyogenic granuloma. Histopathological examination of the lesion showed nests composed of p ..................More
  Transient Acantholytic Dermatosis (Grover's disease)- A case report -
Yu-Wen Cheng, Yao-Kun Chiu, Ji-Chen Ho, Wei-Jen Chen
Dermatol Sinica 18: 229-234, 2000

We herein report a case of transient acantholytic dermatosis (TAD) occurring in a patient with lung abscess. He developed pruritic erythematous papules and papulovesicles on the trunk and upper arms on the fifth hospital day. The histology of skin biopsy showed small circumscribed blisters with a pemphigus vulgaris-like pattern. Under medical treatment, he became afebrile on the tenth hospital day. In the mean time, oral antihistamine and topical steroid cream were prescribed for the skin lesion ..................More
  Verruciform Xanthoma- A case report -
Tzu-Wei Hsieh, Gwo-Shing Chen, Hsin-Su Yu
Dermatol Sinica 18: 235-238, 2000

A 68-year-old male patient presented with a yellowish soft nodule protruding from the skin of the scrotum for several decades. The histopathological study revealed acanthosis, papillomatosis and large amounts of xanthoma cells in the papillary dermis. The diagnosis of verruciform xanthoma was made. No recurrence was detected over a 1-year follow-up period. The clinical and pathologic features, differential diagnosis from other verruciform lesions, the current hypothesis about the pathogenetic me ..................More
  Papular Xanthoma in Children- A case report -
Dong-Jia Tsai, Tien-Yi Tzung, Tsu-Chyang Chen
Dermatol Sinica 18: 239-244, 2000

A 1-year-7-month-old boy had several asympatomatic papular eruptions, particularly on the face, that initially developed at 6 months of age. Individual lesions were yellow to yellow-brownish. New lesions continued to develop over the trunk and limbs in one year. Skin biopsy showed aggregation of foamy histiocytes in the dermis. These cells were positive for CD68, but negative for CD34 and S-100 protein. Periodic acid-Schiff (PAS) stain was negative. Sudan black B and oil-O stains were positive o ..................More
  Combined Nevus-Report of Two Cases-
Kuo-Liang Cheng, Woan-Ruoh Lee
Dermatol Sinica 18: 245-249, 2000

Combined nevus is a unique pigmented lesion of mixed cytological patters. Among the usual attributes are ordinary (nevocellular) nevus cells, pigmented spindle cells, dendritic cells of blue nevus and occasionally epitheloid and spindle cells of Spitz nevus. It tends to be misdiagnosed for its common nevus appearance and its being indistinguishable from other melanocytic lesions without recognition of distinctive phenotypic expressions. We herein report two cases of variants of combined nevi. Mi ..................More
  Superficial Epithelioma with Sebaceous Differentiation
Tsu-Liang Chen, Tsen-Fang Tsai
Dermatol Sinica 18: 250-254, 2000

Superficial epithelioma with sebaceous differentiation (SESD) is a rare, benign, histologically distinct skin tumor. Herein, we describe a 66-year-old female patient who had a pea-sized, brownish, asymptomatic papule over her right postauricular area for about 10 years. The histopathology showed a superficial plate-like growth in reticulated pattern composed of mostly basaloid cells and some squamoid cells with sebocytes studded in the lower portion of the tumor. We report this rare case and rev ..................More
  A Novel Nonsense Mutation at the Human PTCH Gene in a Patient with Nevoid Basal Cell Carcinoma
Kuo-Liang Cheng, Shwu-Fen Chang, Chung-Hong Hu, Woan-Ruoh Lee
Dermatol Sinica 18: 255-259, 2000

The nevoid basal cell carcinoma syndrome (NBCCS) is a highly penetrative but variably expressed autosomal-dominant disorder. The major manifestations are basal cell carcinomas, odontogenic keratinocysts, dyskeratotic pitting of the palms and soles, intracranial calcification, and other developmental skeletal abnomalities. The disorder has been suggested to result from human ptch gene mutation. Here we show a NBCCS patient with a G-to-A substitution at nucleotide 403 position of the ptch gene res ..................More
  Umbilical Omphalomesenteric Duct Polyp
Tzu-Wei Hsieh, Chung-Hsing Chang, Hsin-Su Yu
Dermatol Sinica 18: 260-264, 2000

We report a five-year-old boy complained of occasional odored clear mucoid discharge from umbilicus since birth. A 0.3×0.3 cm2 red polypoid nodular lesion occurred in the umbilical dimple and was associated with frequent mild eczematous changes of the surrounding skin. The histopathological findings revealed some ectopic glandular gastrointestinal epithelium mainly in the upper dermis with focal epidermal defect instead of glandular epithelium. Both carcinoembryonic antigen (CEA) and chromogr ..................More
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