Back issues No.1 - 2001  
  Original Study
  Iontophoretic Local Anesthesia to Ameliorate Painful Intralesional Injection in Treating Keloid
Ya-Hui Chen, Tak-Wah Wong, Hamm-Ming Sheu, Jui-Chen Tsai, Shu-Fen Li
Dermatol Sinica 19: 1-7, 2001

Keloid is a benign over-growth of dermal fibrous tissue during wound healing in predisposed individuals. Though intralesional steroid injection is one of the common effective treatments, many patients were reluctant to this treatment because of the associated pain. We overcome this problem by using lidocaine iontophoretic local anesthesia before injection. Ten female keloid patients, ages ranging from 20 to 45 years (mean 28 years) were enrolled. Two percent lidocaine with 1/80,000 epinephrine w ..................More
  Cutaneous Telangiectases in Neonatal Lupus Erythematosus
Pin-Chi Chiu, Hsien-Ching Chiu
Dermatol Sinica 19: 8-17, 2001

Neonatal lupus erythematosus (NLE), an immune-mediated disease with multisystem involvement in infants, is associated with the transplacental transfer of maternal autoantibodies. Discrete, annular, scaly, erythematous patches and plaques at photo-exposed areas are typical cutaneous lesions of neonatal lupus erythematosus. Cutaneous telangiectasia is also a key feature in neonatal lupus erythematosus. We retrospectively analyzed and followed 13 cases of NLE in National Taiwan University Hospital ..................More
  Case Report
  Hyperkeratosis of Nipple and Areola—A case successfully treated with urea cream—
Po-Yuan Wu, Shing-Fong Horng, Chin-Chou Chen, Jui-Lung Shen
Dermatol Sinica 19: 18-21, 2001

Hyperkeratosis of the nipple and areola is a rare entity with unique clinical manifestations. Clinically the typical lesions are characterized by verrucous thickening and brown pigmentation of the nipple and areola. We report a case of the nevoid form of hyperkeratosis of the nipple and areola with successful treatment by urea ointment. Because the case was not associated with ichthyosis or epidermal nevus, we think it best fits into the category of nevoid hyperkeratosis of the nipple and areola ..................More
  Wuchereria Bancrofti Presented as a Solitary Nodule on Scrotum —A Rare Case Report—
Chih-Hung Lee, Kao-Pin Hwang, Chieh-Shan Wu, Hsin-Su Yu
Dermatol Sinica 19: 22-29, 2001

Wuchereria bancrofti infection is a major cause of lymphatic filariasis. It was mediated by the mosquitoes with infected larva. It has a worldwide range in tropical and subtropical countries, distributing in Africa, Southern-East Asia, Pacific islands, India, northern South America, New Guinea, central America, Turkey, etc. It has been rarely found in Taiwan area after the improvement of hygiene and environment since 1970 with exception in neighboring islands. DEC-added salt in Quemoy islands fu ..................More
  Nevus of Ota Associated with Ocular Malignant Melanoma
Pei-Yu Lo, Dong-Jia Tsai, Nai-Jen Hsu, Tien-Yu Tzung
Dermatol Sinica 19: 30-34, 2001

A 52-year-old male had an asymptomatic blue-gray patch on the right face, scalp, as well as ipsilateral sclera since birth with progressive darkening and nevus of Ota was diagnosed. He received sclera buckling of the right eye due to retinal detachment in 1991. Unfortunately, massive hemorrhage resulted in vision loss of the right eye since then. Persistent high intraocular pressure with epithelial defect and perforation was found subsequently. In 1999, computed tomography of the orbits demonstr ..................More
  Contact Dermatitis with Hypertrophic Scar Formation from Temporary Paint-on Tattoo
Wen-Hung Chung, Chun-Min Wang, Ya-Ching Chang, Hong-Shang Hong
Dermatol Sinica 19: 35-38, 2001

We report a case of allergic contact dermatitis with hypertrophic scar formation following application of a paint-on henna tattoo. A 26-year-old male developed a progressive erythema, edema, itching, and burning on his left arm within 2 weeks after application of a temporary henna tattoo. Patch test revealed positive reaction to paraphenylenediamine (PPD) and henna . After medical treatment, the symptoms subsided, but a hypertrophic scar remained. Henna is a common dye for such a temporary paint ..................More
  Metastatic Crohn's Disease in a 10-year-old Boy —A Case Report—
Yu-Ling Hsu, Hsien-Ching Chiu, Yi-Hwa Liao, Ing-Ruey Chang, Yat-Sen Ho
Dermatol Sinica 19: 39-43, 2001

Inflammatory bowel disease is commonly associated with some cutaneous disorders. We report a case of Crohn's disease combined with a necrotizing granulomatous reaction of the skin in a 10-year-old boy. This child suffered from fever, abdominal pain, watery diarrhea, and several erythematous to violaceous crusted ulcers over bilateral lower limbs and the penis. Colonscopic examination with colon biopsy revealed Crohn's disease. Histopathological examination of the skin lesions showed granulomatou ..................More
  Classical Juvenile (Type III) Pityriasis Rubra Pilaris—A Case Report and Literature Review—
Nan-Lin Wu, Hsiu-Chin Chen, Hsin-Yi Su
Dermatol Sinica 19: 44-51, 2001

Pityriasis rubra pilaris (PRP) is a rare dermatosis and affects both children and adults. At present, the etiology is still not clarified. As for the classification, most discussions are based on the five types classified by Griffiths. As far as the classical juvenile type by Griffiths is concerned, the clinical features are similar to that of classical adult type, but some differences have been mentioned. Now, most reports indicate a favorable prognosis of classical juvenile type, and suggest a ..................More
  Intramural Venous Leiomyosarcoma
Shao-Ping Chang, Tsen-Fang Tsai, Yu-Fu Chen, Hsin-Ho Chen, Chih-Ming Hung
Dermatol Sinica 19: 52-57, 2001

Leiomyosarcomas derive from the venous wall are rare.Their predominant loci are the inferior vena cava and large veins of thighs. The long term survival rates are low,because venous leiomyosarcomas are mostly asymptomatic,early diagnoses and early treatments are difficult.An intramural venous leiomyosarcoma of the distal end of great saphenous vein is presented with the initial symptom of a small painless nodule on the left lower leg of a 58 year-old male patient. ..................More
  Epithelioid Cell Histiocytoma —A Case Report and Review of the Literature—
Wei-Ming Wu, I-Shin Hsih, Heng-Leong Chan
Dermatol Sinica 19: 58-62, 2001

Epithelioid cell histiocytoma (ECH) is a variant of dermatofibroma. It was first described by Wilson Jones in 1989 and less than 100 cases have been reported to date. The clinical manifestation of ECH is usually a polypoid nodule on the extremities. The histopathology is characterized by large and polygonal epithelioid cells in a finely collagenous stroma with focal vascularity. Herein, we present a case here and review the related literature. ..................More
  Erythema Nodosum Migrans Mimicking Cellulitis —Report of a Case—
Yu-Chih Lin, Jau-Shiuh Chen, Hsieng-Ching Chiu
Dermatol Sinica 19: 63-67, 2001

A 69-year-old man with erythema nodosum migrans manifesting one centrifugally spreading, slightly elevated erythematous plaque on the right lower leg is reported. He was initially diagnosed and treated as cellulitis with poor clinical response. A biopsy specimen from this lesion showed classic features of erythema nodosum with lymphohistiocytic infiltration of edematous septae and periphery of fat lobules. Necrosis of vessel walls or fat lobules was not observed. The patient responded to therapy ..................More
  Glomangiomyoma In Multiple Glomus Tumors
Po-Tsang Lee, Chang-Ling Chen, Wen-Jen Wong, Chu-Kwan Wong
Dermatol Sinica 19: 68-74, 2001

Multiple glomus tumors is a rare benign skin neoplasm. According to the arrangement of the skin lesions, it can be simply divided into generalized and localized types. Most of the multiple glomus tumors are sporadic but some are hereditary or congenital. Histopathologically, glomangioma can be found in the majority of the cases. We reported a case of multiple glomus tumors with one lesion showed glomangiomyoma under the pathological examination. This type of pathological finding is very rare but ..................More
  Punctate Porokeratotic Keratoderma (Punctate Porokeratosis): A True Variant of Porokeratosis or A New Entity?—Case Report and Literature Review—
Tsung-Hsien Tsai, Shyh-Dyi Chung, Woan-Ruoh Lee
Dermatol Sinica 19: 75-80, 2001

It is still controversial whether punctate porokeratotic keratoderma (punctate porokeratosis) is a variant of porokeratosis or a new entity. We report on a case of a 25-year-old male with peculiar keratotic plugs on his left palm. The histopathologic findings revealed a cornoid lamellar-like column, under which a reduced-to-absent granular layer was noted. No dyskeratosis or vacuolization of keratinocytes was seen. We try to address an appropriate nosologic designation for this entity by review ..................More
  Granular Cell Tumor
Ta-Sheng Hsu, Fon-Yi Sung, Kai-Yam Ng, Kou-Chang Chou, Ting-An Chang
Dermatol Sinica 19: 81-86, 2001

Cutaneous granular cell tumor is an uncommon skin tumor. However, its histogenesis and differentiation remain controversial. A 40-year-old woman who had an asymptomatic, skin-colored, firm nodule measuring 2cm in diameter on her right arm for about 2 months. She received total excision of the lesion at our hospital. Both histopathological and immunohistochemical examination revealed characteristic change of granular cell tumor. We report this case and review the literature brieftly. ..................More
  Glomangiosarcoma—A Case Report and Review of the Literature—
Shih-Wei Chu, Chieh-Chen Huang, Chung-Tai Yue
Dermatol Sinica 19: 87-90, 2001

Glomangiosarcoma is an extremely rare neoplasm of soft tissue. It originated from a benign glomus tumor. We report a case of glomangiosarcoma occurring on the skin over the left scapular area of a 71-year-old man. The tumor was a dull-red, raised and tender nodule with a maximum diameter of 1 cm. Histologically, the skin lesion revealed a sarcomatous nodule that was surrounded by benign glomus cells at the periphery. In immunohistochemical studies, the tumor cells stained intensely and diffusely ..................More
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