Back issues No.2 - 2002  
  Original Study
  Patch Testing with Fragrance Mix: a 13-year Experience
Hsuan-Hsian Chen Chee-Ching Sun Mei-Ping Tseng
Dermatol Sinica 20: 90-96, 2002

Fragrances are widely encountered in our living environment and are known to be a common cause of allergic contact dermatitis. We have reviewed our patch test data from 1987 to 1999 to establish the pattern of fragrance allergy. During this period, 1,993 patients were patch tested with the European standard series. The positive rate to the fragrance mix was 8.38%. The incidence of fragrance mix allergy was increasing throughout the study period (ρ=0.028). Men were 6.4 years older than that of w ..................More
  Case Report
  Annular Syphilids
Chung-Yee Hui Heng-Leong Chan
Dermatol Sinica 20: 97-104, 2002

Annular syphilid is an uncommon presentation of secondary syphilis, previously seen almost exclusively in blacks. It has not been documented in Taiwan. We reviewed 47 syphilids with pathology records at Chang Gung Memorial Hospital in last 10 year and found six cases of annular syphilids. We concluded that annular syphilid is not uncommon in Taiwan. ..................More
  Tinea Capitis in a Male Adult Caused by Micropsporum Canis —A Case Report—
Wen-Hung Chung Chun-Min Wang Hong-Shang Hong
Dermatol Sinica 20: 105-109, 2002

We report a 70-year-old healthy man with extensive, non-scaling erythema and pustules of total scalp extending to his face and ears. The histopathology revealed many fungal spores in the hair follicles with supurative granulomatous inflammation. The fungal culture was positive for Microsporum canis. Because of prolonged incorrect use of topical steroids, the skin lesion was exacerbated and altered clinically. According to the literature, tinea capitis in adults is supposed to be rare and is mark ..................More
  Demodicidosis in an Immunocompetent Child—A Case Report—
Tzu-Kai Lin Mark Ming-Long Hsu
Dermatol Sinica 20: 110-114, 2002

A 15-month-old healthy female infant has neither congenital immunodeficiency nor immunocompromised condition secondary to liver disease, hyperadrenocorticism, malignancy, or immunosuppressant therapy. She had a 1-week history of erythematous papules at nasal and perioral area. No special family history was revealed. Many Demodex brevis were revealed by 10% KOH preparation of multiple skin scraping. The skin rash cleared after treatment with 10% crotamiton. Similar skin rash recurred 5 months la ..................More
  Giant Cell Collagenoma—A Rare Variant of Sclerotic Fibroma : A Case Report—
Mei-Ching Lee Tseng-Tong Kuo Jing-Yi Lin Heng-Leong Chan
Dermatol Sinica 20: 115-118, 2002

Sclerotic fibroma (Circumscribed storiform collagenoma) is a rare tumor. It may occur sporadically or in the context of Cowden's disease. A new rare variant of giant cell collagenoma was recently described. The new variant showed scattered multinucleated giant cells in an otherwise typical circumscribed storiform collagenoma. Herein, a case of this rare variant occurring in subcutis is reported. ..................More
  Interferon Induced Acute Generalized Exanthematous Pustulosis—A Case Report—
Yen-Chi Chou Lih-Jen Yang Heng-Leong Chan
Dermatol Sinica 20: 119-122, 2002

Interferon is a relatively effective agent in treatment of cutaneous T cell lymphoma, especially in early stage. Many systemic side effects, including skin and appendages, have been reported. This is a case report of a male patient with mycosis fungoides who developed acute generalized exanthematous pustulosis after receiving interferon therapy. ..................More
  Cholesterol Embolism —A Case Report—
Yuh-Ru Huang J.Yu-Yun Lee Hamm-Ming Sheu
Dermatol Sinica 20: 123-127, 2002

We reported a typical case of cutaneous cholesterol embolism (CE) occurring in a 61-year-old female with a history of diabetes mellitus, hyperlipidemia and coronary artery disease for which she received cardiac catheterization and angioplasty 3 months previously. Two months after catheterization, she developed multiple painful, erythematous and purpuric reticulate lesions on her both soles with shallow ulceration on her left sole. Pathological examination revealed a small artery in reticular der ..................More
  Occupational Radiodermatitis: an Accidental Overexposure to Ir192 Gamma Rays
Chein-Hui Hung Gwo-Shing Chen Hsin-Su Yu Hung-Yi Chuang
Dermatol Sinica 20: 128-135, 2002

An industrial radiographer was accidentally exposed to a high dose of ionizing radiation from an Ir192 source during radiography of weldjoints in oil pipelines. Skin erythema, swelling, ulceration developed within 3 days, leading to progressive tissue deterioration. The dose to the whole body was estimated to be about 2-4 Gy, and the dose to the fingertips was approximately 52 Gy. He visited a medical practitioner who approached conservatively including local skin care with dressings. The woun ..................More
  Epidermolysis Bullosa Herpetiformis(Dowling-Meara) with the Presenting Sign as Congenital Localized Absence of Skin
Fang-Chi Liu Hsiu-Chin Chen Hsin-Yi Su Chin-Yuan Tzen
Dermatol Sinica 20: 136-141, 2002

We herein present a male newborn who had one 7x8cm2, sharply-demarcated ulcer covered by a glistening membrane over the medial aspect of the left ankle and part of the dorsal foot at birth. Multiple variable-sized blisters and erosions, mainly distributed over bilateral hands, feet and periungal areas developed soon after delivery. Biopsy of the blister showed subepidermal bulla with mild perivascular inflammatory infiltration in the upper dermis. Ultrasrtuctural study revealed intraepidermal bl ..................More
  Fibroepithelioma of Pinkus—A Case Report —
Yu-Hua Lee Hsin-Yi Su Hsiu-Chin Chen
Dermatol Sinica 20: 142-146, 2002

An 81-year-old man presented with an asymptomatic, flesh-colored, slightly lobulated, pedunculated tumor on the left thigh for 2 years. Histopathological examination revealed anastomosing cords of basaloid cells with peripheral palisading embedded in a delicate fibrous stroma. Some clefts between aggregations of the basaloid cells and adjacent stroma were also noted. Furthermore, focal follicular cyst and trichoblastoma-like structures were noted. According to these findings, fibroepithelioma of ..................More
  Lyme Disease During Pregnancy—A Case Report—
Hung-Chieh Tsai Chin-Fang Lu Chien-Ming Shih Li-Lian Chao Chung-Hong Hu
Dermatol Sinica 20: 147-151, 2002

We herein report the first laboratory-confirmed case of Lyme disease during pregnancy in Taiwan. A 32-year-old woman developed multiple expanding annular erythematous skin lesions during the first trimester of pregnancy. Lyme disease was diagnosed based on the clinical manifestations, and seroreactivity against Borrelia burgdorferi. The skin lesions gradually resolved after intravenous penicillin treatment. She subsequently delivered a full-term female infant with no congenital defects. ..................More
  Multiple Erythema Migrans Treated with Minocycline Accompanied with Jarisch-Herxheimer Reaction
Li-Na Tung Hsin-Yi Su Chieh-Ming Shih Li-Lian Chao Hsiu-Chin Chen
Dermatol Sinica 20: 152-160, 2002

We herein present a 29-year-old male who had multiple lesions of erythema migrans. An unusual presentation of severe erythematous swelling of face with vesicular, exudative, crusted, and scaling change over it was noted. Lyme disease was diagnosed according to the travel history, clinical manifestations, and serological findings. Following treatment with minocycline, he developed headache, malaise, soreness of neck and waist, and exacerbation of the skin lesions accompanied with some new lesions ..................More
  Resident Forum
  Grouped Keratotic Papules along the Blaschko's Lines on Back
Wan-Ting Chiu Shu-Ling Hu Ming-Tuo Chuan Yih-Ying Wu
Dermatol Sinica 20: 161-162, 2002

一位37歲男性病患16年前開始在左側背部出現會癢的丘疹。他發現熱、流汗及陽光曝晒會誘發丘疹產生,並使癢感加劇,這些病兆在冬天時會稍微緩解但未完成消除。病人健康狀況良好,無任何家族病史與其他系統性疾病。經身體檢查,發現在病人的左側背部有呈線狀排列且群聚的紅棕色角化丘疹,腋下、會陰部、口腔粘膜、手掌、足蹠及指甲完全正常。 ..................More
  Erythematous Papules on The Eyelids of a 45-year-old Japanese Man
Yu-Ying Chen Mei-Eng Tu Hsiu-Chin Chen Hsin-Yi Su
Dermatol Sinica 20: 163-164, 2002

一位45歲的日本籍男性前來本院就診,自述5個月前於兩側眼瞼出現了一些不痛不癢的紅棕色丘疹,之後的幾個月內,臉頰處亦出現了類似的皮膚病灶,病患曾自行至藥房購買不明的外用藥品,但卻無任何的改善,於是前來本院就疹。病人的健康情況大致良好,實驗室檢查亦無異常發現,皮膚學檢查發現在病患兩側下眼瞼及臉頰、額頭處有一些針頭狀大小,呈對稱性分佈,無症 ..................More
  An Asymptomatic Cervical Nodule in a 20-year-old Man
Yi-Ming Huang Woan-Ruoh Lee
Dermatol Sinica 20: 165-166, 2002

Case report: A 20-year-old man presented with an asymptomatic cervical nodule present since birth. The patient was healthy without other medical history. The nodule increased in size gradually over recent two years. On phydical examination, a 20x8mm elastic, flesh-colored, elongated subcutaneous nodule was located at the anterior portion of the left sternocleidomastoid muscle, approximately 10mm above its sternal insertion.(Fig. 1a, 1b). The nodule caused a 4x5mm, cone-shaped out-pouching of the ..................More
  Bullous Dermatosis Associated with a Mediastinal Tumor and Several Autoantibodies
Chang-Yu Tsai Chieh-Hsun Chen Heng-Leong Chan Tseng-Tong Kuo
Dermatol Sinica 20: 167-168, 2002

A 31-year-old woman suffering from bullous dermatosis since half a year ago was found to have several autoantibodies (anti-intercellular substance Ab 1:40, ANA 1:1280, homogenous type and anti-dsDNA Ab 429 IU/ML) recently. Physical examination revealed multiple flaccid bullae and erosions on face, trunk and limbs (Fig. 1). A skin biopsy taken from her neck was sent for histologic and DIF study (Fig. 2 and 3). She was also found to have a mediastinal tumor on her chest X-ray and CT (Fig. 4). Her ..................More
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