Back issues No.3 - 2002  
  Original Study
  The Study of Cutaneous Malignancies in Renal Transplant Recipients-Southern Taiwan Experience
Wen-Wei-Feng Ji-Chen Ho Chao-Hua Chuang Hwai-Ho Hsieh
Dermatol Sinica 20: 169-179, 2002

Skin cancer is the most common cancer among renal-transplant recipients in Western studies, but in Taiwan the related information appears limited. We studied a population-based cohort of 286 renal-transplant recipients in southern Taiwan between 1981 and 1999, in order to identify the incidence and distribution of cancers. Sixteen of the 286 renal-transplant recipients developed malignancies. The distribution of malignancies deriving from renal transplant recipients in southern Taiwan appears to ..................More
  Tinea Capitis in Eastern Taiwan:An Analysis of 28 Cases
Wen-Lee Kuo Jer-En Chiang
Dermatol Sinica 20: 180-185, 2002

We diagnosed 28 cases of culture-proven tinea capitis in eastern Taiwan between July 1991 and February 2001. The patients included 11 children and 17 adults, from 1 to 79 years old. There were 25 females and 3 males. All the 3 male patients were boys. The median age was 5 years for children and 61 years for adults. Microsporum canis was the most common isolated dermatophyte (9 cases), followed by Trichophyton violaceum (8 cases), Trichophyton tonsurans (5 cases), Trichophyton rubrum (4 cases) an ..................More
  Case Report
  Werner's Syndrome—A Case Report and Mutation Analysis—
Guan-Yu Chen Hamm-Ming Sheu
Dermatol Sinica 20: 186-191, 2002

Werner's syndrome is an autosomal recessive disorder causing premature aging and cancers. A 33-year-old male suffered from unhealing wound on right foot for 2 years. He looked older than his age, with short stature, light body weight, thin hair, balding of beard, high-pitched voice, bird-like face, atrophy of the subcutaneous fat tissue, calluses on the sole, toe nails dystrophy, cataract, diabetes mellitus, and hypogonadism. Linkage analysis revealed that the WS gene (WRN) was localized to th ..................More
  Cutaneous Protothecosis—Report of 5 Cases and Review of the Literature—
Chia-Hui Hung Hung-Wen Kuo Yu-Wen Cheng Yao-Kun Chiu Ji-Chen Ho
Dermatol Sinica 20: 192-199, 2002

Cutaneous protothecosis is an uncommon infection caused by achlorophytic, algae-like unicellular organisms of the genus Prototheca. It was first described by Kruger in 1894 and less than 80 cases have been reported since 1964. It occurs mainly in the immunocompromised patients, otherwise asymptomatic and self-limited cutaneous lesions may be seen in healthy patients. Herein, we present five protothecosis cases with histologically charateristic morula. They aged from 48 to 74 years (3 females, 2 ..................More
  Dissecting Cellulitis of the Scalp—Clinicopathologic Analysis of Eight Cases and Literature Review—
Fu-Fang Hsieh Mark Ming-Long Hsu J.Yu-Yun Lee
Dermatol Sinica 20: 200-206, 2002

Dissecting cellulitis of the scalp is an uncommon, chronic, progressive suppurative disease that predominantly affects black men and only rarely seen in Orientals or Whites. We reported the clinicopathologic findings of 8 cases diagnosed in the National Cheng-Kung University Hospital (NCKUH) from 1988 to 2001, the largest series to date. The patients were all young men between 17 and 26 years of old, mean 20.6 years. All presented with painful, fluctuant nodules and abscesses with hair loss main ..................More
  Cutaneous Manifestations of Disseminated Candidiasis in Leukemic Patients —Report of 3 Cases—
Chang-Yu Tsai I-Hsin Shih Chin-Fang Lu
Dermatol Sinica 20: 207-213, 2002

Recognition of the characteristic cutaneous lesions of disseminated candidiasis may allow early diagnosis and treatment of this often fatal fungal infection. This report discussed three leukemic patients with cutaneous manifestations of disseminated candidiasis due to Candida tropicalis. Single or multiple erythematous papulonodules with a purpuric center were seen on the trunk and 4 extremities. In most reported cases of disseminated candidiasis with skin lesions, the diagnosis can be confirmed ..................More
  Acral Syringoma—A Case Report—
Cha-Chi Chang Sen-An Yang Kun-Bow Tsai Gwo-Shing Chen
Dermatol Sinica 20: 214-217, 2002

Although syringoma is a common adnexal tumor, acral presentation is very rare. We report a case of multiple acral syringomas that appeared as symmetrical grouped, slightly pigmented papules limited to the dorsum of both hands in a young woman. This clinical presentation should be included in the differential diagnosis of papular lesions on the hands. ..................More
  Classical Kaposi's Sarcoma of the Glans Penis Effectively Treated with Low-dose Intralesional Vinblastine Injection—A Case Report—
Shu-Fen Lee Tak-Wah Wong J.Yu-Yun Lee
Dermatol Sinica 20: 218-222, 2002

Classical Kaposi's sarcoma (KS) is a multicentric cutaneous and extracutaneous vascular neoplasm predominantly affecting older individuals, immunosuppressed patients and homosexual men. Although KS of the genitalia is not rare event, it is challenging to treat multiple KS of the glans penis. Localized KS may be treated by excision, radiation, cryotherapy and intralesional injection of interferon-alpha or cytotoxic chemotherapy. Although intralesional injection of vinblastine has been used to tr ..................More
  Congenital Fascial Dystrophy: A Variant of Stiff Skin Syndrome
Chih-Jung Hsu Cheng-Hsiang Hsiao Chun-Hsiang Chang Li-Fang Wang
Dermatol Sinica 20: 223-228, 2002

Congenital fascial dystrophy (a variant of stiff skin syndrome) is a rare scleroderma-like genetic disorder characterized by stony-hard skin, limited joint mobility and flexural contracture of the limbs. The onset is at birth, and the disease occurs without sclerodactyly, telangiectases, nail fold changes and visceral involvement. We report a typical case to illustrate the clinical and pathologic findings of a patient with this disorder. To our knowledge, this is the first case of this disorder ..................More
  Eosinophilic Panniculitis—A Case Report and Literature Review—
Wan-Ting Chiu Hon-Ru Yu Ming-Tuo Chuan Yih-Yiing Wu
Dermatol Sinica 20: 229-233, 2002

Eosinophilic panniculitis, characterized by a prominent infiltration of subcutaneous fat with eosinophils, is a rare panniculitis. Atopy, allergy, arthropod assault, Streptococcus infection, gnathostomiasis, autoimmune disease, and malignancy may be the associated disorders. We herein present a 22-year-old male with recurrent, itchy and tender erythematous swelling of his chin for 2 years. The histopathology of lesional skin biopsy revealed infiltration of numerous eosinophils in the subcutaneou ..................More
  Lipodermatosclerosis Complicating Deep Vein Thrombosis—A Case Treated with Stanozolol—
Li-Na Tung Hsin-Chi Chen Hsin-Yi Su
Dermatol Sinica 20: 234-240, 2002

A 21-year-old male had noted two slowly enlarging, hyperpigmented sclerotic patches on his left leg and ankle respectively for more than one year; in the meantime, the lesion on the ankle progressed into a poor-healing deep ulcer gradually. He had a history of deep vein thrombosis of left thigh occurring about three years ago. The diagnosis of lipodermatosclerosis was established on the basis of clinical manifestation, histopathology and immunofluorescence examination. After six weeks of stanozo ..................More
  Phakomatosis Pigmentovascularis Type Iib with Patent Umbilical Vein and Inferior Vena Cava Hypoplasia
Pei-Yu Lo Tien-Yi Tzung
Dermatol Sinica 20: 241-247, 2002

Phakomatosis pigmentovascularis (PPV) is characterized by coexistence of capillary malformation and various melanocytic lesions. Herein, we reported a case of PPV type Iib with patent umbilical vein and, to our best knowledge, this condition has never been described before. This 20-year-old male had nevus of Ota, aberrant Mongolian spots and extensive port-wine stain. He suffered form Sturge-Weber syndrome with left eye blindness, mild mental retardation and epilepsy. Brain computed tomography d ..................More
  Superficial Acral Fibromyxoma
Yu-Lin Chang Hon-Ru Yu Ming-Tuo Chuan Yih-Yiing Wu
Dermatol Sinica 20: 248-252, 2002

A 33-year-old male had suffered from one mildly tender dome-shaped protruding mass measuring 0.8x0.8x0.5cm in size over the tip of the right index finger for about 3 months. Histopathologically, the dermis showed loose storiform arrangement of collagen bundles in a myxoid matrix, with spindled or stellate-shaped fibroblast-like cells, moderately accentuated vasculature and an increased number of mast cells. The overlying epidermis revealed hyperkeratosis and acanthosis. The diagnosis of superfic ..................More
  Majocchi's granuloma caused by Trichophyton rubrum in a renal transplant recipient—A Case Report and Review of Literature—
Po-Yuan Wu Cheng-Yi Liu Shing-Fong Horng Jui-Lung Shen
Dermatol Sinica 20: 253-257, 2002

A 31-year-old male who received renal transplantation due to chronic renal failure more than one year ago, presented with several dark reddish-brown subcutaneous nodules on the dorsum of his toes and left lower leg for 1 month. A skin biopsy specimen revealed an inflammatory granulomatous reaction, and several fungal hyphae were revealed by periodic acid-Schiff stain. Trichophyton rubrum was isolated 3 weeks after fungal culture of the skin tissue and pus. He received terbinafine 250mg treatment ..................More
  Resident Forum
  Multiple Brownish to Black Papules in a 13-year-old Boy
Yi-Ming Huang Woan-Ruoh Lee
Dermatol Sinica 20: 258-259, 2002

Case report A 13-year-old boy was found to have multiple brownish to black papules over neck, shoulder, abdomen and back since 1995. He was diagnosed with cerebellar medulloblastoma in 1991.Total tumor excision was done. Six courses of adjuvant chemotherapy with vinblastine, VP-16 and cisplatin were administered later. A huge recurrent tumor over the right temporal lobe with mass effect was noted in 1994. The patient underwent total recurrent tumor removal. Adjuvant craniospinal irradiation was ..................More
  Velvety Hyperpigmented Plaques on the Dorsa of Bilateral Hands, Feet and Flexural Aspects of Wrists in a 21-year-old Man
Yu-Hun Lee Hsin-Chi Chen Hsin-Yu Su
Dermatol Sinica 20: 260-261, 2002

病例報告 一位21歲男性,主訴在其手背、足背、手腕屈側和腳踝周圍,出現棕黑色粗厚的斑塊,大約已有五年之久。病灶於夏季較為嚴重,冬季則較緩解。病人並無自覺症狀,但因游泳時病灶會由棕黑轉為白色,甚為明顯而深感困擾。家族中並無其他成員有類似病變。 理學檢查發現於手背、足背、手腕屈側和腳踝周圍的皮膚,有對稱性分布之棕黑色絨毛樣增厚(Fig. 1),特別是 ..................More
  Progressive Unilateral Facial Depression in a 9-year-old Girl
Cheng-Sheng Hung Tsen-Fang Tsai Yu-Fu Chen Chih-Ming Hung
Dermatol Sinica 20: 262-263, 2002

病例報告 一位九歲的小妹妹,近兩年來在前額及左下巴附近,出現略為塌陷且暗深色的斑塊,由於照像時不美觀且有逐漸變深向外擴大的傾向,遂被父母帶至本院皮膚科求診。 臨床檢查,在額頭處,有線形凹陷變化的病灶,在同側下巴附近,亦有三角形色深且凹陷。(Fig. 1)。患者並未有自覺排汗異常現象。理學檢查,表皮並無脫皮或發紅現象,也無萎縮現象。經觸摸患部, ..................More
  Multiple Pruritc Hyperkeratotic Papules in a Patient with End-stage Renal Disease
Chang-Yu Tsai Chieh-Hsun Chen Heng-Leong Chan Tseng-Tong Kuo
Dermatol Sinica 20: 264-265, 2002

A 51-year-old man, a hepatitis-C virus carrier with diabetes and end-stage renal disease, was referred to the Dermatology Clinic with a 3-month history of pruritic eruption involving the scalp initially, gradually increasing in number, and becoming generalized. He had a poor-controlled DM for more than 20 years and was complicated by diabetic retinopathy, which was treated by photo-coagulation. He was hypertensive and in end-stage renal failure in 1999. He started hemodialysis since then. In Sep ..................More
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