Back issues No.4 - 2002  
  Original Study
  Vulvar Syringoma-- A Study of Fifteen Cases--
Yu-Huei Huang Ya-Hui Chuang Hong-Shang Hong Tseng-Tong Kuo
Dermatol Sinica 20: 266-270, 2002

Syringoma, a benign adnexal tumor, mainly occurrs on the periorbital area of middle-aged women. Syringomas involving the vulva are rare. Only sporadic case reports could be found in the literature. The purpose of our study was to analyze the clinicopathologic features of fifteen cases of vulvar syringoma diagnosed at Chang Gung Memorial Hospital for the past 10 years. Clinically, their age of onset ranged from 19 to 55 years with a median age of 29 years. Most of our patients complained of a v ..................More
  Pyoderma Gangrenosum: A Comparison of the Idiopathic Group,the Parainflammatory Group, and those Associated with Hematological Disorders. ----- Review of 13 Cases -----
Chia-Chen Wang Hsin-Chun Ho Heng-Leong Chan
Dermatol Sinica 20: 271-279, 2002

Pyoderma gangrenosum (PG) is an uncommon, ulcerated cutaneous disorder of unknown etiology. Approximately 50% of the patients have associated diseases, among which arthritis and inflammatory bowel disease are the most common. We retrospectively review 13 patients (6 male, 7 female) of PG from 1987 to 2001 with an emphasis on the comparison of clinical presentations and courses of the idiopathic group (IPG), the parainflammatory group (PPG) and those ssociated with hematological disorders (HPG). ..................More
  The Antinociceptive Effect of Transdermal EMLA delivery using sonophoresis
Yi-Fang Lee Han-Nan Liu
Dermatol Sinica 20: 280-285, 2002

Many procedures performed by dermatologists require prior administration of a local anesthetic agent to prevent painful sensation experienced by patients. EMLA is a frequently used topical anesthetic agent with the disadvantage of considerable application time before analgesia takes effect. Sonophoresis has been used to enhance the absorption of topical analgesics. In this study twenty one volunteers with a median age of 33 years were enrolled to receive topical and sonophoresis-aided EMLA cream ..................More
  The Minimal Erythema Dose of 311 nm Narrow-band UVB in Taiwanese
Yi-Ying Chen Tsen-Fang Tsai
Dermatol Sinica 20: 286-293, 2002

Background: The therapeutic effectiveness of 311 nm narrow-band UVB over the traditional broad-band UVB in the treatment of psoriasis has been established. However, the minimal erythema dose (MED) to UVB within this particular spectrum in Taiwanese is not yet known. Objective: Our purpose was to investigate the MED of 311 nm narrow-band UVB in Taiwanese. Methods: Irradiation with 311 nm narrow-band UVB was performed over the lower back in 13 patients with psoriasis and 9 healthy volunteers. The ..................More
  Case Report
  Self-Healing Juvenile Cutaneous Mucinosis
Ya-Yi Chang Gwo-Shing Chen Hsin-Su Yu
Dermatol Sinica 20: 294-298, 2002

Self-healing juvenile cutaneous mucinosis (SJCM) is a new entity distinct from previously described forms of cutaneous mucinosis. We present a 9-year-old girl who had asymptomatic skin lesions for 8 months. Examination revealed multiple, flesh colored 2-3 mm papules on the bilateral knees, thighs, wrists and dorsal hands. Histopathological examination of the skin lesion showed a large amount of alcian blue ( pH2.5) positive mucin deposited between the collagen bundles of the reticular dermis. No ..................More
  Mammary Areolar Leiomyoma with Bizarre Nuclei
Shu-Fen Lee Yu-Yun Lee
Dermatol Sinica 20: 299-302, 2002

Cutaneous leiomyomas are benign smooth muscle tumors. Pleomorphic nuclei are seen in its unusual variant, leiomyoma with bizarre nuclei. Dartoic leiomyomas are originated in the dartos muscles of the genitalia, mammary areola, and nipple. Leiomyomas of the mammary areola are rare. In this report, we describe a very rare example and the first case of mammary areolar leiomyoma with bizarre nuclei. The patient was a 51-year-old man who noted a firm, brownish, polypoid nodule on the areola of th ..................More
  Linear Punctate Porokeratosis
Yu-Lin Chang Hon-Ru YU Ming Tuo Chuan
Dermatol Sinica 20: 303-307, 2002

A 17-year-old woman presented with a linear hyperkeratotic plaque surmounted with numerous, firm, tiny, 1-2 mm protruding keratotic plugs surrounded by a thin, raised margin, on the volar surface of the left thumb and index finger, since early childhood. Histopathologic examination showed typical cornoid lamellae. Accordingly, she was diagnosed as linear punctate porokeratosis. We herein report this uncommon case and review the literature briefly. ..................More
  Congenital Ectodermal Dysplasia: Report of Two Sporadic Cases
Ming-Yao Lai Tien-Yi Tzung
Dermatol Sinica 20: 308-312, 2002

Case one is a 6-year-old girl. She had sparse scalp hair and eyebrows at birth, which totally lost over time. Besides, all her 20 nails were dystrophic with palmoplantar keratoderma. Her teeth and sweating function were normal. Based on the above-mentioned findings, hidrotic ectodermal dysplasia (Clouston syndrome) was diagnosed. Case two is a 5-year-old boy. He suffered from scanty scalp hair and eyebrows since birth with widely spaced conical teeth and anhidrosis. In addition, a characteristic ..................More
  Neutrophilic Eccrine Hidradenitis in a Patient with Endstage Renal Disease
Kung-Kai Lin Gwo Shin Chen Roger Chin-Che Hsu
Dermatol Sinica 20: 313-317, 2002

'Neutrophilic eccrine hidradenitis (NEH) is an uncommon, self-limited dermatosis with a variable clinical presentation. It is most commonly seen in patients receiving chemotherapeutic drugs for treatment of malignant disease. Neutrophilic infiltrate in and around eccrine coils together with necrosis of eccrine epithelium is the histologic hallmark of this isease. We report a case with end-stage renal disease undergoing continuous ambulatory peritoneal dialysis, who developed recurrent erythemato ..................More
  Secondary Merkel cell Carcinoma in Skin Donor Site?—A case report—
Cha-Chi Chang Shih-Tsung Cheng Gwo-Shing Chen Hsin-Su Yu
Dermatol Sinica 20: 318-323, 2002

Merkel cell carcinoma (MCC) is an uncommon cutaneous neoplasm that mainly occurs solitarily in the head and neck region of the elderly. Systemic metastasis to distant organs, such as liver, lung, bone, and brain, is common. However, secondary occurrence of the tumor cells to skin donor site has not been reported previously. We reported one case that a "secondary"MCC appeared in the split-skin donor site on the contralateral thigh. The mechanism of this "secondary"MCC still remains unknown. We pr ..................More
  Treatment of the vulva lesion by carbon dioxide laser and mutation Analysis of ATP2C1 Gene in a Patient with Hailey-Hailey Disease
Ya-Ming Tsai Mei-Hui Yang Sheau-Chiou Chao
Dermatol Sinica 20: 324-328, 2002

A 37 year-old woman suffered from pruritic, keratotic papules over the vulva for 1 month and condylomata acuminata was clinical suspected. Typical lesions of Hailey-Hailey disease (HHD) in the inguinal areas and axillae were noted and diagnosed about 4 to 5 years ago. Microscopic studies revealed suprabasal acantholysis ("dilapidated brick wall") from the vulva lesion. A Human papillomavirus stain was negative. The vulva lesion was treated by carbon dioxide (CO2) laser vaporization, and no recur ..................More
  Keratoderma Plantaris and Mechanic's Hands as the Initial Presentation in a Case of Dermatomyositis
Lih-Yuan Chang Lih-Jen Yang Yeong-Jian Jan Wu
Dermatol Sinica 20: 329-334, 2002

A 64-year-old woman initially presented with itching and fissuring hyperkeratotic plaques on the ventral and lateral sides of fingers and toes with extension to both palms and soles. A Body weight loss of 4kg was also complained. Tentative diagnosis of acquired palmoplantar keratoderma was made. The patient responded quite well to Acitretin 25mg daily. She underwent a malignancy survey, which was negative. Unfortunately, progressive proximal muscle weakness occurred three months later. Itching e ..................More
  The Many Faces of Superficial Basal Cell Carcinoma -Clinicopathological and Immunohistochemical Studies of Three Different Lesions
Kuo-Hsieh Wang Chia-Lang Fang Chien-Chung Lai Woan-Ruoh Lee
Dermatol Sinica 20: 335-343, 2002

Superficial basal cell carcinoma is a distinct variant of basal cell carcinoma not only histologically but also biologically. Its indolent growth and occasionally misleading clinical presentation can sometimes pose a diagnostic challenge to clinicians. In this report, we describe three lesions of superficial basal cell carcinoma in two Taiwanese patients. Their clinical appearances were drastically different from each other. The histopathology of the three lesions varied in the aspects of the tu ..................More
  Chondrodysplasia Punctata-A Case Report -
Yu-Huei Huang Sindy Hu I-Hsin Shih Hong-Shang Hong Tseng-Tong Kuo
Dermatol Sinica 20: 344-348, 2002

Chondrodysplasia punctata is an unusual inherited disorder. We report such a case in a 7-day-old girl presenting with ichthyosiform erythroderma at birth. The patient also had facial dysmorphism and bilateral asymmetric shortening of the upper limbs. A skin biopsy specimen showed hyperkeratosis, follicular keratosis in the dilated follicular ostia, and calcium deposits in the stratum corneum. Radiologic examination revealed asymmetric shortening of humeri and femora and numerous punctate calcifi ..................More
  Resident Forum
  A Localized Recurrent Erythematous Plaque on the Left Dorsal Foot in a 24-year-old Woman
Cheng-Sheng Hung Tsen-Fang Tsai Yu-Fu Chen Chih-Ming Hung
Dermatol Sinica 20: 349-350, 2002

病例報告 一24歲女性,主訴三星期前在左足背上,出現一塊環狀紅色斑塊具微癢及疼痛,之後 紅色斑變得稍微隆起浮腫,數天後,紅斑塊中央區慢慢緩解及皮膚顏色變深,邊緣處出 現針頭樣細小膿皰丘疹及細薄皮屑。據其自述,在過去三年中,相似病灶在足背相同位置, 反覆出現。理學檢查發現,病灶呈現弧狀隆起紅斑,中央略有色素沉澱,隆起紅班邊緣有針頭大小脫屑 ..................More
  Symmetric Crops of Vesicles on an Erythematous Base over the Bilateral Flanks in a 43-year-old Man
Yu-Hua Lee Hsin-Chi Chen Hsin-Yi Su
Dermatol Sinica 20: 351-352, 2002

病例報告 一位43歲男性,主訴從五年前開始,在兩側腰部出現對稱性分佈、劇癢的小水泡,數週後症狀會自然緩解,每年都會發作一至二次,但這次發作二週以來,因症狀特別厲害而來求診。理學檢查發現於兩側腰部皮膚出現對稱性伴紅色基底的群集狀小水泡(Fig. 1),病人其他部位皮膚正常。實驗室檢查包括血液常規和生化檢驗皆在正常範圍。我們從右側腰部做皮膚切片檢查(F ..................More
  An Eroded Papule on the Right Labium Majus in a 35-year-old-woman
Fang-Chi Liu Hsin-Chi Chen Hsin-Yi Su Hsiu-Chin Chen
Dermatol Sinica 20: 353-354, 2002

CASE REPORT A 35 year-old female patient presented with an asymptomatic nodule on her right labium majus for 3 months; she ever received once liquid nitrogen cryotherapy and once electrocauterization for it, respectively. However, due to the persistence of this lesion, she went to our OPD for help. On physical examination, one well-circumscribed, umbilicated nodule was observed at the inner face of right labium majus. It was 1 cm × 0.8 cm in size. ( Fig. 1) On palpation, it was freely mobil ..................More
  Horizontal Hyperpigmented Bands on Thumbnails and Black Tongue in a 37-year-old Female with Breast Cancer
Wen-Hung Chung Ching-Chi Chi Shu Hui Wang Hsin Chun Ho
Dermatol Sinica 20: 355-356, 2002

病例報告:一位三十七歲,左乳房患有浸潤性管狀癌(infiltrating ductal carcinoma)併有淋巴轉移的女性,其他的理學檢查及血液生化檢查皆正常,並沒有貧血的現象。病人開始接受 Doxorubicin/cyclophosphamide/5-fluorouracil 的化學治療一個月後,其雙手拇指的指甲弧影(lunula)上緣處開始出現水平帶狀的黑色素沉著( Fig 1)。 此外,在化療期間,病人的舌部也逐漸地出現了黑色素沉著現象(Fig 2)。 ..................More
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