Back issues No.4 - 2004  
  A Comparative Survey of Historical Taiwanese Dermatologic Vernacular and Academic Terminology-The Task force to Develop an Indigenous Dermatologic Language Curriculum and Lexicography
Shih-Tsung Cheng, Chiao-Li Ke, Hok-Chu Tiu Roger , Chin-Che Hsu

English Abstract Twenty to thirty percents of disputes between physicians and patients are due to ill communication. Inept command in indigenous Taiwanese languages may play an important role. Inadequacy of Taiwanese language education in medical schools, scarcity of research in Taiwanese medical vernacular terms, and lack of standardization in Taiwanese medical terminology further complicate the problems. In the first part of this article, we record histologic Taiwanese dermatologic academic a ..................More
  Original Study
  Liver Pathology Resulting from Therapeutic Dose of Terbinafine in Rats
San-Duo Chen, Chi-Chung Chou, Ming-Chih Chou, William Bell, C. Howard Tseng, Jen-Hung Yang
Dermatol Sinica 22 : 274-280, 2004

Abstract Terbinafine has been suggested as the treatment of choice for dermatophyte onychomycosis, and has excellent tolerability in treated patients. Hepatic injury has been reported with the use of terbinafine, however, the mechanism of hepatotoxicity is still obscure. The present study was designed to investigate the pathology of the liver in rats following administration of the therapeutic dose of terbinafine 4 mg/kg bw p.o., daily. The hemogram and biochemistry including liver enzymes w ..................More
  Subcutaneous panniculitis-like T-cell lymphoma: a clinical, pathological and immunophenotypic analysis of 10 Taiwanese cases
Cheng-Sheng Chiu, I-Hsin Shih , Hong-Shang Hong, Tseng-tong Kuo
Dermatol Sinica 22 : 281-286, 2004

Background Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare variant of peripheral T-cell lymphoma of the skin. In practice, it is most likely to present to a dermatologist. However, apart from individual case reports, detailed studies of SPTCL are limited in dermatology literature from Taiwan. Objectives To describe the clinical, pathological and immunophenotypic features of 10 Taiwanese patients with SPTCL. Patients and methods The medical records of all patients diagnosed ..................More
  Case Report
  A Case Report of Microcystic Adnexal Carcinoma Treated With Mohs Micrographic Surgery
Perng-Nian Chu , Kuo-Liang Cheng , Kuo-Hsien Wang , Yun-Ho Lin , Woan-Ruoh Lee
Dermatol Sinica 22 : 301-305, 2004

Microcystic adnexal carcinoma is a rare cutaneous appendageal malignancy, which is characterized by local aggressiveness. Histopathologically and immuno-histopathologically, the tumor reveals mixed eccrine and pilar differentiation. To date, Mohs micrographic surgery provides a more effective therapy and better outcome than traditional wide excision. We report a 66-year-old male with a slowly growing whitish indurated plaque approaching his left nasolabial area for at least 20 years. A diagnosti ..................More
  Ulcerative Lichen Planus—Case Report and Review of the Literature
Chia-Cheng Wu , Chia-Yu Chu , Shiou-Hwa Jee
Dermatol Sinica 22 : 306-311, 2004

Ulcerative lichen planus of the feet is a rare variant of lichen planus. We report a case presenting with chronic painful ulceration of the feet and cicatricial changes of the toenails. The pathology of the ulceration showed diagnostic of lichen planus. She also had typical lichen planus on the dorsal hands. The ulceration was resistant to many kinds of topical agents, but completely healed within 2 months of dapsone treatment. The clinical manifestations and treatment responses of this disease ..................More
  Bizarre parosteal osteochondromatous proliferation:A case report with literature review
Chi-Fu Kao, Yang-chih Lin, Yu-Hung Wu, Be-Fong Chen
Dermatol Sinica 22 : 312-316, 2004

We report the case of a 12-year-old female with a slowly erythematous enlarging nodule on her right big toe. Its characteristic radiographs and the histopathologic findings exhibited classic Bizarre parosteal osteochondromatous proliferation (BPOP) features. We review the relevant literature and discuss the clinical manifestations, pathology and differential diagnosis of this lesion. ..................More
  Primary Cutaneous Angioplasmocellular Hyperplasia-Case Report
Chung-Chu Wang , Yu-Hung Wu , Yang-Chih Lin
Dermatol Sinica 22 : 317-320, 2004

ABSTRACT Primary cutaneous angioplasmocellular hyperplasia was first described by Gonzalez in 1995 as an asymptomatic, non-ulcerated, slightly umbilicated and violaceous nodule. To the best of our knowledge, only one additional case has been reported since the first two cases. We describe the first two patients in Taiwan. A 39-year-old man had a painless, erythematous, approximately 1-cm nodule with a dark red halo on the lower back. A 35-year-old woman presented with a friable nodule that bled ..................More
  Pigmented Extramammary Paget’s Disease
Mei-ju Ko, Cheng-Hsiang Hsiao, Chung-Jen Tseng, Yi-hua Liao
Dermatol Sinica 22 : 321-326, 2004

Abstract Extramammary Paget’s disease (EMPD) usually presents as an erythematous, scaly patch with crusts, or superficial erosions. Pigmented EMPD is a rare variant of EMPD that may mimic malignant melanoma clinically and histopathologically. We report a case of pigmented EMPD on the genital region. The 58-year-old man had an erythematous, scaly patch with a pigmented macule on the scrotum for 5 years. Histopathological and immunohistochemical examinations of the pigmented region confirmed EM ..................More
  Cutaneous phaeohyphomycosis caused by Exophiala jeanselmei-Successful treatment with the combination of itraconazole, topical heat followed by additional cryotherapy
Hung-Hsu Yang, Hsiu-Chin Chen, Yu-Hung Wu, Yang-Chih Lin, Pei-Lun Sun
Dermatol Sinica 22 : 327-332, 2004

Phaeohyphomycosis caused by Exophiala species have recently been reported with increasing frequency with wide-spread use of immunosuppressive agents and improved laboratory methods for making the diagnosis. However, no standard therapeutic regimens have been established to date. Often, treatment is frustratingly prolonged, especially for larger lesions when surgery is not feasible. We report a case of cutaneous verrucous phaeohyphomycosis caused by Exophiala jeanselmei in a 75-year-old female. ..................More
  Hemochromatosis- A Case Report
Chien-Te Lin, Cha-Chi Chang, Gwo-Shing Chen
Dermatol Sinica 22 : 333-337, 2004

Abstract Hemochromatosis is a disorder of chronic iron overload associated with tissue injury resulting from iron deposition. Typical findings include cirrhosis of liver, a bronze-brown pigmentation of the skin, diabetes mellitus, and cardiomyopathy. We describe a 46-year-old female patient presented with generalized bronze-brown pigmented skin with prominence over sun-exposed area for about 10 years. Diabetes mellitus and chronic hepatitis C history were traced, and she denied blood transfu ..................More
  Cutaneous Penicillium marneffei Infection and Mycobacterial Spindle Cell Pseudotumor in a Patient with Rheumatoid Arthritis-A Case Report?
Chao-Chun Yang, Julia Yu-Yun Lee, Mark Ming-Long Hsu
Dermatol Sinica 22 : 338-344, 2004

ABSTRACT Penicillium marneffei infection is characterized by disseminated and progressive clinical course and mainly involves the skin, blood, bone marrow and lymph nodes with fever, anemia and weight loss. Mycobacterial spindle cell pseudotumor (MSP) is a peculiar and very rare form of mycobacterial infection mainly caused by Mycobacterium avium-intracellulare (MAI), and most commonly affects lymph nodes. MSP resembles spindle cells neoplasm pathologically and may be easily misdiagnosed. Both ..................More
  Resident Forum
  Multiple Targetoid Patches on the Face, Shoulder and Forearms in a 27-year-old Female
Chung-Yang Yen, Jui-Lung Shen, Jen-Hang Yang
Dermatol Sinica 22 : 345-346, 2004

CASE REPORT A 27-year-old Chinese female presented with several reddish patches with target-like appearance, over the face, shoulder, and both forearms for 2 weeks (Fig.1). In the meanwhile, fever to 38.5℃ with general malaise, and arthragia over left elbow and knee were first noted for 2 weeks. There was no past history of herpes simplex virus infection. She had neither taken medications nor respiratory tract infection prior to the onset of the facial rashes. In the clinical examination, ..................More
  A Well-defined, Non-encapsulated Tumor Composed of Delicate Spinedle Cell in the Lower Extremity
Hsin Huang , Chao-Hong Liu , Shu-Rung Shei , Tzei-Yi Lin
Dermatol Sinica 22 : 347-348, 2004

Case Report A 30-year-old woman had a slowly but progressively enlarging nodule on her right lower legs for more than 3 years. No neurological symptoms or signs were noted. The detailed dermatological finding revealed a well-defined, smooth-contured, immovable, flesh-colored, and rounded nodule, with firm consistency, located in the deep skin. (figure 1) A yellowish-white, ovoid mass measuring 1.4x1.2x1.0cm3 was excised. Microscopically, it showed a well-defined, non-encapsulated nodule in th ..................More
  Two Erythematous Nodules on the Left Ear in a 9-Month-Old Female Infant
Tsung-Hua Tsai, Hsiu-Chin Chen, Yu-Hung Wu, Yang-Chih Lin
Dermatol Sinica 22 : 349-350, 2004

CASE REPORT A 9-month-old, full-term, healthy female infant presented with a 1-month history of skin eruptions on her left auricle. There was no other specific medical history. On examination, there were two erythematous shiny nodules on her left ear (Fig. 1). One on the antihelix was 7 mm in size with an ulceration in the center. The other was on the helix and was 2 mm, with a smooth surface. The larger nodule was excised with the specimen submitted for pathology examination (Fig. 2). Ac ..................More
  Generalized Erythematous to Violaceous Papules and Confluencing Patches with Vesiculobullous Lesions in a 53-year-old man
Chien-Kuan Lee, Lin-Hui Su, Hsien-Ching Chiu, Cheng-Hsiang Hsiao, Ying-Jui Chang1, Yu-Ling Hsu
Dermatol Sinica 22 : 351-352, 2004

Case report A 53-year-old man, an alcoholic, developed itchy, scaling erythematous patches on large areas of the face, scalp, V area of the anterior neck and extensor extremities. Three months later, many tense vesicles and bullae followed by ulcers developed over his neck, abdomen (Fig. 1) and upper limbs. Besides, a widespread erythematous to violaceous papules and confluencing patches on the trunk, Gottron’s papule-like lesions on the extensor surface of finger joints (Fig. 2), elbows and ..................More
  A Slow Growing Grayish Nodule near the Nasal Bridge after Chemocauterization
Ming-Hsien Lin, J. Yu-Yun Lee, Tak-Wah Wong
Dermatol Sinica 22 : 353-354, 2004

Case Report A 60-year-old woman visited dermatology clinic, National Cheng Kung University Hospital. She presented with a well-demarcated dermal nodule on the left side of the nasal bridge (Fig. 1). The nodule grew slowly since 4 years ago after she had received a chemocauterization to remove a pigmented lesion, conceived as a nevus herself on the same area. The procedure was performed by a street vendor. Neither complication nor recurrence of the lesion was noted after the chemocauterization. ..................More
  A non-tendered subcutaneous nodule over the heel of a 9 months old baby girl
Ming-Yi Tseng, Kuo-Chia Yang, Julia Hui-Mei Chang
Dermatol Sinica 22 : 355-356, 2004

CASE REPORT A 9 month-old baby girl visited our out patient clinic due to a bean-sized lump on her left foot since birth. A 2x2 cm flesh-colored movable nodule without tenderness on her left heel was noted. There was not any other skin lesion with her. There were no family histories, congenital anomalies, traumatic histories or previous insect bites, either. We excised the nodule under local anesthesia. The histopathology of the specimen was shown in figure 2 and 3. No local recurrence was ..................More
  A 60-year-old Woman with Many Erythematous Papules on the Face, Neck, Back and Upper Extremities, and Arthralgia over Hands
Yu-Ting Chen, Hao-Chiung Lin, Chieh-Chen Huang, Yuh-Yu Chou
Dermatol Sinica 22 : 357-358, 2004

CASE REPORT A 60 year-old woman visited our out-patient clinic and complained of many itchy skin lesions over the face, neck, back and upper extremities for about 3 months. Dermatological examination showed many 1-3mm, erythematous papules, some of which with underlying erythematous patches, were found over the face, post-auricular areas, neck, upper chest, bilateral forearms and back. In addition, painful swelling and erythema of the joints were noted for one month on bilateral hands, especial ..................More
  Facial papulopustules after topical treatment with pimecrolimus
Shiou-Han Wang, Rong-Yi Jang, Chun-Ping Wu, Tsen-Fang Tsai
Dermatol Sinica 22 : 359-360, 2004

A 24-year-old girl had atopic diathesis with allergic rhinitis and sinusitis. Several erythematous pigeon egg-sized, ill-defined itching scaly patches were found on the cheeks and chin since more than 1 year ago. She visited a local clinic and some topical agents with unknown contents were applied on the lesions. However, the condition aggravated and the lesions extended to her nose, forehead and eyelids. Half a year later, she visited the other dermatologist and rosacea was diagnosed, and metro ..................More
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