Back issues No.4 - 2008  
  Diagnostic Immunopathology in 21ST Century Dermatology Part II: Basement Membrane and Vascular Reactions
Maria Jasmin J. Jamora
Dermatol Sinica 26: 191-227, 2008

Immunofluorescence techniques in dermatology involve the detection of autoantibodies directed against target antigens in human skin. Direct and indirect immunofluorescence, salt split skin technique, immunoelectron microscopy and immunoblotting remain relevant and often fi rst-line diagnostic tools. Recently developed enzyme linked immunosorbent assays (ELISA) which utilize recombinant proteins to detect serum antibodies demonstrate high sensitivity and specifi city in many skin conditions. ..................More
  Original Study
  Histological Analysis of 10 Cases of Cutaneous Sarcoidosis in Taiwan
Chin-Yi Su Han-Nan Liu
Dermatol Sinica 26: 228-235, 2008

Naked sarcoidal granulomas are supposedly characteristic, but not pathognomonic of sarcoidosis. Other types of histopathological pattern can also happen in sarcoidosis and may lead to misdiagnosis. Thirteen archival skin specimens taken from 10 patients were retrieved from our fi le for study. All patients were labeled as sacroidosis based on histological evidence of noncaseating granuloma found in skin or conjunctival biopsies, characteristic chest x-ray fi ndings, and lastly excluding oth ..................More
  Case Report
  Seasonal Recurrence of Linear Darier’s Disease -A Case Report
Feng-Ling Lin Shu-Lin Hu Cher-Wei Liang
Dermatol Sinica 26: 236-241, 2008

Darier’s disease is an uncommon autosomal dominant genodermatosis. About 10% Darier’s diseases present a mosaic form with linear distribution following Blaschko’s lines. This unusual forms were named localized, linear, unilateral, segmental or zosteriform Darier’s disease. We reported a case of linear Darier’s disease in a 52-year-old female. She had recurrent keratotic yellow-brown papules over her right lower extremity every summer for thirty years and the skin lesions resolved ..................More
  Recurrent Infl ammation of Incontinentia Pigmenti in a 30-year-old Woman
Hsuan-Wen Hsiao Chi-Liang Chang Hsuan-Hsiang Chen Yi-Hua Liao
Dermatol Sinica 26: 242-247, 2008

Incontinentia pigmenti (IP) is an X-linked dominant disorder with a complex multisystemic and developmental phenotype. Classically, the skin lesions occur perinatally in four successive stages: infl ammatory vesicular (stage 1), verrucous (stage 2), hyperpigmented (stage 3), and scarring (stage 4), along the lines of Blaschko, refl ecting the somatic mosaicism of X-chromosome inactivation in female patients. In general, the lesions of stage 1 IP begin perinatally and clear completely within ..................More
  Pachydermodactyly-A Case Report
Yu-Lin Yeh Horng-Shin Lin Yu-Ping Hsiao Hung-Chun Shih Bor-Jeng Tsai Jen-Hung Yang
Dermatol Sinica 26: 248-251, 2008

Pachydermodactyly is a rare form of digital fi bromatosis characterized clinically by asymptomatic soft tissue swelling affecting the skin of the lateral aspect of the proximal interphalangeal joints of the fi ngers in young boys around puberty. We herein report a 20-year-old healthy male with characteristic manifestations of pachydermodactyly. ..................More
  Lipidized Fibrous Histiocytoma Presenting as a Keloid-Like Lesion-A Case Report
Feng-Ling Lin Mei-Chin Ho Shu-Lin Hu
Dermatol Sinica 26: 252-257, 2008

A 46-year-old man presented with a gradually growing nodule on the left dorsal foot, which had been present for over 10 years. In the beginning, the lesion was treated as a keloid. Because of poor response to treatment, biopsy was arranged. Sections showed a dermal tumor composed of numerous foamy cells, hyalinized wiry collagen, spindle cells and entrapped collagen. The foamy cells were positive for KP1(CD68) and negative for S-100 protein and HMB-45. The histological and immunohistochemic ..................More
  IgA Pemphigus: Subcorneal Pustular Dermatosis Type- A case report with vesicle and pustular eruption for 13 years cured with dapsone in 3 weeks
Yung-Chuan Liu Tien-Yi Tzung Chi-Bin Lin Pei-Yu Lo
Dermatol Sinica 26: 258-263, 2008

IgA pemphigus is a newly characterized group of autoimmune intraepidermal blistering diseases presenting as vesiculopustular eruptions with a predilection in axillary and groin areas. Immunopathologically, IgA deposition in the intercellular space of the epidermis is present in all cases of IgA pemphigus by direct immunofluorescence. However, unlike pemphigus vulgaris, IgA pemphigus carries a relatively benign course. Herein we reported a case of subcorneal pustular dermatosis type IgA pemp ..................More
  An Eccrine Porocarcinoma with Bowenoid Features on the Neck
Chuan-I Liu Shu-Lin Hu Cher-Wei Liang Ming-Tuo Chuan
Dermatol Sinica 26: 264-266, 2008

An 80-year-old male visited our outpatient clinic with the presence of a progressively enlarging eczematous plaque over the right neck close to the post-auricular area for 2 years. The skin lesion was unresponsive to cryotherapy and topical steroids. At this presentation, the physical examination revealed a ten dollar coin-sized, polygonal, salmonred firm plaque with erosions and crusts, accompanied with a pinkish small nodule which was located in the center of the plaque (Fig. 1). Un ..................More
  Resident Forum
  Unusual Diffuse Hair Loss
Jonathan Te-Peng Tseng Tsung-Hsien Tsai
Dermatol Sinica 26: 267-268, 2008

A 35-year-old Taiwanese man reported gradual diffuse hair loss on his scalp and bilateral eyebrows for 2 months. He had had chronic urticaria for more than 4 years. He denied taking new medications or having been ill during the preceding 6 months. He denied having unprotected sex or having been exposed him to any blood or serum products. Two months prior to the manifestation of hair loss, he had a transient generalized maculopapular eruption which occurred 1 day after receiving an infl uenz ..................More
  An Erythematous Patch on Glans Penis
Hung-Yi Huang Tsen-Fang Tsai
Dermatol Sinica 26: 269-270, 2008

The 76 year-old uncircumcised male noticed an asymptomatic pea-sized erythematous patch on his glans penis 9 months ago. He received some topical medication over the lesion from the local clinics but there was no improvement. The lesion progressed in size gradually. He visited local hospital 2 months ago and an incisional biopsy was performed. The pathological result revealed erythroplasia of Queyrat. Topical imiquimod cream 5% was prescribed. However, pain and erosion occurred after the us ..................More
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