Back issues No.3 - 2009  
  Vascular Tumors of Intermediate Malignancy:A Review and Update
Jason S. Stratton, Steven D. Billings
Dermatol Sinica 27: 140-153, 2009

Vascular tumors of intermediate malignancy encompass a broad range of histologic entities. They are characterized clinically by having a high risk of local recurrence and limited risk of regional or distant metastasis. Vascular tumors of intermediate malignancy frequently present in the skin and often cause diagnostic diffi culty. This article reviews the clinical and histologic features of kaposiform hemangioendothelioma, epithelioid hemangioendothelioma, Dabska tumor, retiform hemangioend ..................More
  Original Study
  Differentiating Basal Cell Carcinoma from Trichoepithelioma by Using Androgen Receptor Expression
Yu-Fen Lee, Yun-Ting Chang, Han-Nan Liu
Dermatol Sinica 27: 154-160, 2009

Background: To distinguish a basal cell carcinoma (BCC) from a trichoepithelioma (TE) can be diffi cult even for an experienced dermatopathologist. Objective: In this study, we sought to reconfi rm the androgen receptors (AR) immunostaining pattern of BCC and TE and to determine whether AR immunoreactivity could serve as a useful maker to differentiate these two tumors. Methods: Twenty-one cases of circumscribed BCC, solid type and nineteen cases of TE were obtained from the fi les of the ..................More
  Inconsistent Immunostaining and Racial Difference in Extramammary Paget’s Disease
Fu-Chiang Chiang, Szu-Ying Chu, Yun-Ting Chang
Dermatol Sinica 27: 161-169, 2009

Background: Extramammary Paget’s disease (EMPD), an uncommon neoplastic disorder, usually presents as an eczematous patch on the apocrine-rich area. It can be further classifi ed into primary and secondary EMPD by its association with underlying malignancies. The histopathology shows a characteristic intraepidermal atypical clear cell infi ltrate. Objective: To determine whether the histopathologic or immunohistochemical features of EMPD could be used to predict clinical behavior or assoc ..................More
  Case Report
  Application of Allele-Specifi c Polymerase Chain Reaction for Rapid Differentiation of Mycobacterium Leprae from Mycobacterium Tuberculosis
Yu-Ta Yen, Yu-Wen Cheng, Wei-Ming Wu
Dermatol Sinica 27: 170-175, 2009

Leprosy (Hansen’s disease) is a chronic granulomatous infection caused by Mycobacterium leprae affecting primarily skin and nerves. Leprosy is an important clinical problem and is also a challenging diagnostic problem for clinicians. Clinically, leprosy might at times be diffi cult to be distinguished from lupus vulgaris. We report a 70-year-old woman who showed a well-demarcated erythematous enlarging plaque on left peri-ocular region suggesting leprosy resembling lupus vulgaris. Skin bi ..................More
  Langerhans Cell Histiocytosis Presented as Generalized Vesiculo-Pustules in a Neonate
Yu-Fen Lee, Ding-Dar Lee, Han-Nan Liu
Dermatol Sinica 27: 176-180, 2009

A one-month-old female baby had been noted to have multiple vesicles and pustules over the head, face, trunk and four extremities since she was one-week-old. Under the impression of disseminated herpes virus infection, intravenous acyclovir was given after admission. Serum herpes simplex virus and varicella zoster virus enzyme-linked immunosorbent assay test and virus culture were all fruitless, although herpes simplex virus-1 was vaguely identifi ed in direct fl uorescent staining of lesio ..................More
  A Solitary Halo Neurofi broma
Ming-Ya Mao, Meng-Tse Wu, Hsu-Jung Hsieh, Tze-Yi Lin, Po-Yuan Wu
Dermatol Sinica 27: 181-185, 2009

Halo neurofi broma is a rare benign tumor. In the past, 3 cases of multiple halo neurofi bromas and 1 case of a solitary halo neurofi broma have been reported. The neurofi broma is characterized by a skin-colored, dome-shaped soft papule or a nodule surrounded by hypopigmented macules. The pathogenesis of neuroectodermally derived tumors associated with halo phenomenon is still poorly understood. We report a case of a 46-year-old female with a solitary halo neurofi broma and discuss the pos ..................More
  Two Cases of Multiple Eccrine Hidrocystomas with Good Response to Botulinum Toxin
Ta-Ju Liu, Ji-Chen Ho
Dermatol Sinica 27: 186-191, 2009

Multiple eccrine hidrocystomas of the face are rare benign cystic lesions characterized by numerous asymptomatic, fl esh-colored, mild, and translucent facial papules in middle-aged women. The condition often runs a chronic course, which may be exacerbated by seasonal change or heat exposure. Topical application of 1% atropine is the conventional treatment option, but the results are not always satisfying. Here, we present the clinicopathological features of and treatment modality for two m ..................More
  Photo-Induced Sarcoidosis
Yu-Ping Hsiao, Han Chang, Meng-Chuan Ho, Lien-Chuan Yang,, Jen-Hung Yang
Dermatol Sinica 27: 192-195, 2009

A 61-year-old woman, who was a farmer, suffered from fl esh to reddish annular skin rash over face, trunk and the extremities on and off for more than 20 years. The eruptions initially occurred on the face, and then involved the neck, chest, upper back and dorsal aspects of upper limbs indicating sunexposed areas. The lesions revealed as annular, erythematous, shiny-surfaced, infi ltrated papules or plaques (Fig. 1). The physical examination revealed no abnormal fi ndings on chest, an ..................More
  Detection of Human Papillomavirus Type 31 in a Case of Papillated Bowen’s Disease
Jeng-Feng Chen, Bai-Yao Wu
Dermatol Sinica 27: 196-198, 2009

A 74-year-old male visited our clinic because of an asymptomatic skin lesion on the inner aspect of left thigh, which he had noticed for one year. He denied any history of arsenic ingestion, immunosuppressive therapy or radiotherapy. Past history was unremarkable. There are no lesions suspicious for human papillomavirus (HPV) infection during whole body skin examination. His wife was recently under gynecologic and dermatologic check-up and there is no evidence suggestive of HPV infect ..................More
  Resident Forum
  A Painless Mass on the Upper Arm
Shih-Wei Yeh, Kuo-Hsien Wang, Chung-Hong Hu, Woan-Ruoh Lee, Hsiou-Hsin Tsai
Dermatol Sinica 27: 199-200, 2009

A 92-year-old male patient presented with a 3-year history of an enlarging, painless mass on the right arm (Fig. 1). He did not have any history of trauma on the area. The patient reported no weight loss and had no other symptoms other than rapid enlarging of the tumor for the last 6 months. Physical examination showed an 8 x 5 cm fl esh colored, fi rm, ill-defi ned mass on right arm (Fig. 1). No cervical or axillary lymphadenopathy was noted. The MRI showed a huge illdefi ned soft tissue m ..................More
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