Back issues No.3 - 2012  
  Original Study
  Genotype distribution of human papillomavirus in anogenital warts of male patients in Taiwan
Yu-Pin Cheng , Chieh-Wen Chen , Yi-Shuan Sheen , Tsen-Fang Tsai

Background Reports on the prevalence of different human papillomavirus (HPV) genotypes in male patients with anogenital HPV infection are limited. Methods We retrospectively analyzed the HPV genotypes of 100 consecutive patients seen in our department with anogenital HPV infection during 2003–2006. History was gathered from the medical records. Results The most common HPV genotypes among Taiwanese male patients for check of anogenital warts (in descending order) were HPV 6 (46%), HPV ..................More
  The role of protozoa in the etiology of chronic urticaria
Aziz Ramazan Dilek , Nursel Dilek , Yunus Saral , Saliha Eks¸ i

Background Urticaria is a condition characterized by short-lived swellings of the skin, mouth, and genitalia due to transient leakage of plasma from small blood vessels into the surrounding connective tissues. Although infectious agents such as bacteria and virus causing acute urticaria have been reported previously, very little research has been carried out to understand the relationship between parasitosis and urticaria. This study was designed to contribute to the understanding of the relati ..................More
  Case Report
  Pachyonychia congenita: Report of two cases and mutation analysis
Jia-Ming Yeh, Ching-Yuang Huang, Sheau-Chiou Chao

Pachyonychia congenita (PC) comprises a group of rare autosomal dominant genetic disorders that involve ectodermal dysplasia. It is characterized by hypertrophic nail dystrophy, focal palmoplantar keratoderma, follicular keratoses, and oral leukokeratosis. Historically, PC has been subdivided into two subtypes, PC-1 or PC-2, on the basis of clinical presentation. However, differential diagnosis based on clinical grounds, especially in young and/or not fully penetrant patients, can be difficult. ..................More
  Intra-arterial angiolymphoid hyperplasia with eosinophilia of the temporal artery: Report of two cases and review of the literature
Hao-Tien Hsiao, Yu-Hung Wu

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a relatively common benign vascular disorder of uncertain etiology and has many synonyms, such as pseudopyogenic granuloma, atypical pyogenic granuloma, epithelioid hemangioma, and histiocytoid hemangioma. It usually develops on the head and neck, manifesting as reddish-to-dark purpuric papules or nodules. In this article, we report two patients who had uncommon intra-arterial ALHE that occurred in the temporal artery. In both cases, the ALHE ..................More
  A case of cutaneous clear cell sarcoma determined by clinicopathological and cytogenetic analysis
Yung-Ting Chuang, Tze-Yi Lin, Chih-Jung Hsu
DERMATOLOGICA SINICA 30 (2012) 101-104

Cutaneous clear cell sarcoma (CCS) is a rare soft tissue malignancy that typically manifests in the distal extremities of young adults. Although it shows melanocytic differentiation, CCS is clearly pathologically and genetically distinct from malignant melanoma. Here, we report the case of a 43-year-old male who had an asymptomatic, deep-seated, slowly enlarging, firm mass over the right heel for 30 years that recently and rapidly progressed with tenderness. We arranged for the total excision of ..................More
  Hypopigmented large-cell acanthoma of the eyelid
A. Tulin Mansur, Ikbal E. Aydingoz, Ali Kupelioglu, Emel Dikicioglu Cetin
DERMATOLOGICA SINICA 30 (2012) 105-107

Large-cell acanthoma is an asymptomatic, slightly keratotic, usually hyperpigmented epidermal lesion that is mostly seen in the sun-exposed skin of middle-aged or elderly people. It is characterized by extraordinarily large keratinocytes that can reach up to twice their normal size without a change in the nucleus/cytoplasm ratio. Here, we describe a chronic case of large-cell acanthoma that involved the whole upper eyelid of a 67-year-old man for at least 15 years. The lesion was almost depigmen ..................More
  New-onset guttate psoriasis following intravesical immunotherapy of Bacillus Calmette–Guerin
Chih-Tsung Hung, Wei-Ming Wang, Chih-Wei Tsao, Chien-Ping Chiang
DERMATOLOGICA SINICA 30 (2012) 108-111

Intravesical Bacillus Calmette–Guerin (BCG) is usually a well-tolerated treatment for urethelial carcinoma of the bladder. A 60-year-old male endured multiple erythematous white-scaled maculopapules over his trunk, back, and four extremities after 2 months of the 6-weekly intravesical instillation of BCG. Skin biopsy revealed parakeratotic hyperkeratosis, intracorneal neutrophilic Munro's abscess, and acanthosis. Guttate psoriasis was diagnosed, and he was treated successfully with topical ste ..................More
  Good therapeutic outcome of radiotherapy in large facial skin cancers
Yi-Pei Lee , J. Yu-Yun Lee , Helen H.W. Chen , Tak-Wah Wong , Forn-Chia Lin , Yuan-Hua Wu
DERMATOLOGICA SINICA 30 (2012) 112-114

Introduction Reports of treating large facial skin cancers by radiotherapy are scant. 1, 2, 3 Complete resolution of a huge exophytic angiosarcoma of the central face could be achieved by radiotherapy with relapse-free survival of 5 years.3 In this report, we describe two cases of large squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) treated by radiotherapy with good clinical and cosmetic results. Although these tumors might be amenable to conventional surgery or Mohs micrographic ..................More
  Resident Forum
  Multiple erythematous erosive papules and nodules on the perianal area of an 84-year-old bedridden woman
Yung-Yi Lee, Jui-Hung Ko, Yi-Chin Shih
DERMATOLOGICA SINICA 30 (2012) 115-116

Case report An 84-year-old woman presented with a 6-month history of multiple painful cutaneous papulonodules on the buttocks and perianal area. She had underlying dementia and was bedridden. She had urine incontinence and encopresis for>10 years. The patient initially developed papules around the anus. She did not undergo any systemic or topical treatment, and the papules gradually enlarged to papulonodules after 6 months. Her family did not report any history of topical skin contact. Physica ..................More
  Multiple erythematous nodules with a necrotic center in a patient with acute lymphoblastic leukemia
Yu-Wen Yeh, Wei-Ming Wang
DERMATOLOGICA SINICA 30 (2012) 117-118

Case report A Taiwanese man 20 years of age presented with neutropenic fever, dyspnea, and generalized skin eruptions after receiving chemotherapy for the management of acute lymphoblastic leukemia (Figure 1A). The chemotherapy regimen was given for 6 months but discontinued due to the profound pancytopenia, in which the absolute neutrophil count (ANC) was below 100/mm3. Multiple discrete painful skin eruptions started to develop 2 months later. The initial presentation of skin lesions was mul ..................More
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