Back issues No.1 - 2013  
  Editorial View
  Changes to Dermatologica Sinica in 2013
Chia-Yu Chu

This year marks another exciting new beginning for Dermatologica Sinica. Changes include not only new Editors but also the appointment of new members from France, Germany, Japan, Korea and USA for the Journal's International Advisory Board and Editorial Board. They will play an important role in contributing to the development of Dermatologica Sinica and soliciting more articles from international researchers, leading to the maximum possible dissemination and recognition of Dermatologica Sinica ..................More
  Evidence-based dermatology
Ching-Chi Chi

Evidence-based medicine (EBM) has become a hot topic in medical practice, education, and research. However, a large number of senior doctors did not have an opportunity to learn EBM in medical schools. Firstly, this article addresses the history of EBM and the principle of practicing EBM, i.e., asking, acquiring, appraisal, application, and auditing. Secondly, this article also provides a brief introduction to evidence-based dermatology and compares the introduction of clinical practice guidelin ..................More
  Original Study
  Nail disorder among patients on maintenance hemodialysis
Malihe Charkhchian, Akram Beheshti, Amir-Abdollah Zangivand, Afsaneh Sedighi

Background/Objective Chronic renal failure can lead to nail disorders. The aim of this study was to investigate nail disorders and laboratory data in patients on constant hemodialysis (HD) in a hospital in Qazvin, Iran. Methods A case-controlled study was performed. End stage renal disease patients (n = 149) undergoing regular HD and 147 randomly selected individuals were examined for nail disorder. All participants were examined by two trained students and a single dermatologist. Specific ..................More
  Safety and effectiveness of adalimumab in patients with moderate-to-severe psoriasis who had inadequate therapeutic response to prior etanercept
Ting-Shun Wang, Tsen-Fang Tsai

Background Few studies exist that evaluate the therapeutic response among switchers of tumor necrosis antagonists in patients with psoriasis, especially Asian patients. Objective This study aimed to evaluate the safety and effectiveness of adalimumab in patients with moderate-to-severe psoriasis who had inadequate therapeutic response to prior etanercept. Methods This is a single-center, open-labeled, retrospective study on the effects of adalimumab in patients with moderate-to-severe p ..................More
  Dyschromatosis symmetrica hereditaria: A retrospective case series and literature review
Amy Chia-Ying Peng, Yi-An Chen, Sheau-Chiou Chao

Background/Objective Dyschromatosis symmetrica hereditaria (DSH) is a rare pigmentary genodermatosis characterized by hyper- and hypopigmented macules on the face and dorsal aspects of the extremities. This study aimed to delineate the unique clinical, histological, and genetic features of DSH in a Taiwanese population. Methods A retrospective review of clinical charts and archival photographs was performed for patients diagnosed with DSH in a medical center in Taiwan between 1992 and 2011. ..................More
  Case Report
  Pulmonary Mycobacterium abscessus infection-induced erythema induratum
Chin-Yin Liu, Horng-Shin Lin, Yu-Ping Hsiao, Yuan-Ti Lee, Jen-Hung Yang

Erythema induratum (EI) is clinically characterized by recurrent crops of tender nodules on the lower legs and lobular panniculitis with granulomatous inflammation and pathologically characterized by vasculitis and focal fat necrosis. Currently, many authors consider EI to be a multifactorial disorder with diverse causes, including Mycobacterium tuberculosis and hepatitis C infection. Here, we report a case of a 65-year-old female with a 1-year history of recurrent crops of tender nodules and pl ..................More
  Primary cutaneous CD30+ anaplastic large-cell lymphoma in a young patient with psoriasis
Ming-Chun Chen, Di-Qing Luo

Psoriasis is a common chronic inflammatory cutaneous disease, while primary cutaneous CD30+ anaplastic large-cell lymphoma (PC-ALCL) is a rare T-cell lymphoma which always has an excellent prognosis, although multifocal PC-ALCL tends to relapse after systemic chemotherapy. Psoriasis associated with PC-ALCL is exceptionally rare. We report a 29-year-old Chinese female with a 5-year history of psoriasis treated with Chinese herbs alone, who was referred to our institution with a tumor on the left ..................More
  Ossifying fibromyxoid tumor – A case report
Chin-Chun Chen, Tsung-Ming Tsai, Tzu-Hsuan Liu, Kuo-Chia Yang, Hui-Ju Yang, Tzu-Cheng Su, Pei-Yi Chu

Ossifying fibromyxoid tumor (OFMT) is a rare soft tissue tumor of uncertain histogenesis, occurring predominantly in deep soft tissues of the extremities. Typically, OFMT presents in adults on the extremities or trunk, as a deep soft tissue mass. Less appreciated is the fact that OFMT may also present as a mass in the superficial subcutis or dermis. We herein report a female who presented with an asymptomatic subcutaneous nodule on the left thigh for 3 years, and who was diagnosed as having typi ..................More
  Intravascular fasciitis of the scalp: A case report
Yi-Hsin Hsiao, Cheng-Sheng Chiu

Case report A healthy 24-year-old woman presented with an asymptomatic and rapidly growing swelling on the scalp that had been present for 3 months. Clinical examination revealed a 3 cm × 2.5 cm, movable, firm, and deep-seated subcutaneous nodule on her occipital scalp (Figure 1). No irritation or erosion was noted. There was no history of previous trauma, insect bites, or nodule drainage. A schwannoma was suspected clinically and surgical excision performed. Histopathological examination re ..................More
  Generalized lichenoid tattoo reaction with spontaneous resolution after skin biopsy
Hsin-Yu Fang, Po-Yuan Wu, Hsu-Jung Hsieh

Introduction Tattooing has been practiced for thousands of years in many parts of the world and it is increasingly popular in today's society, particularly among the young people. Decorative tattooing involves the introduction of tattoo pigments into the dermis. Cutaneous reactions to tattoos are common and are generally due to the salts or metals in the pigments and may occur from weeks to years after the procedure. Welander first described reactions to tattoos in 1893.1 Different reactions t ..................More
  Resident Forum
  Mottled hyperpigmentation on the face and neck of a woman 35 years of age
Chih-Tsung Hung, Hong-Wei Gao, Bai-Yao Wu, Chien-Ping Chiang

A Taiwanese woman 35 years of age presented with asymptomatic, mottled hyper- and hypopigmented macules on her neck and face, which had presented in the last 2 years. Spotted macules were first noted on her neck and had slowly progressed to involve her face as time went by. Her medical history was unremarkable. She did not have photosensitivity or any other systemic or cutaneous diseases before the onset of the lesions. There were no family members with similar cutaneous presentations. Examinati ..................More
  Rapidly progressing, painful, ulcerative changes in long-standing psoriasiform plaques in a 46-year-old man
Sheng-Yiao Lin, Tsu-Man Chiu, Kuo-Chia Yang, Chuan-Cheng Wang, Ming-Ching Shen, Pei-Yi Chu, Yueh-Min Lin

A 46-year-old man was admitted to a community hospital with fever and rapidly progressing, painful, ulcerative skin lesions. He was transferred to our hospital for further examination. According to his medical history, he had been diagnosed with psoriasis, but this was not confirmed by a skin biopsy. The generalized pruritic plaques on his trunk and extremities had waxed and waned for several years but had exacerbated during the previous year. Skin examination on admission showed diffuse redness ..................More
  Recurrent ulcers on a hypertrophic lower extremity since childhood
Kuei-Chung Liu, Chao-Chun Yang

A 68-year-old woman with underlying hypertension came to our clinic for a progressively enlarging ulcer (10.5 × 6 cm) with occasionally active and projectile bleeding on her right dorsal foot for 5 months. The ulcer recurred several times on the same area since teenager years and resulted in indurated and fibrotic skin. Her right lower extremity became progressively hypertrophic with the presence of varicose veins since her childhood. At the time of her visit to our clinic, there were prominent ..................More
  Isolated erythematous plaque on the right cheek
Ting-Shun Wang, Tsen-Fang Tsai

A 54-year-old man without underlying disease had one mild itchy rash on the right cheek for 6 months. He tried topical fluocinolone acetonide ointment and the lesion became less itchy. However, the rash enlarged gradually, so he came to our clinic. Cutaneous finding was a 4 × 5 cm, erythematous-to-brownish plaque on the right cheek with focal erosions. No lesions were found elsewhere (Figure 1A). A skin biopsy was done, which revealed acantholytic cells mainly in the granular layer and nonspeci ..................More
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