Back issues No.3 - 2014  
  Original Study
  Dermatological conditions in patients with brain damage
Joon Lee, Sang-Hyeon Hwang, Ji-Hye Park, Won-Serk Kim
DERMATOLOGICA SINICA 32 (2014) 133-136

Background As a result of the focus on vital functions in patients with brain damage, dermatological symptoms are often overlooked during their period of admission to hospital. However, patients with brain damage are more likely to have dermatological diseases than the general population and other inpatients for various reasons, including immobilization, treatment with multiple drugs, long-term hospitalization, and their immunocompromised status. Objectives The purposes of this study were: ..................More
  Acute generalized exanthematous pustulosis: A retrospective study of 51 cases in Taiwan
Yung-Yi Lee, Wen-Hung Chung
DERMATOLOGICA SINICA 32 (2014) 137-140

Background/Objective Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse drug reaction characterized by fever and numerous sterile non-follicular pustules. It is mainly attributed to drugs, although other factors have been implicated. The objective of this study was to evaluate the clinical and histological features of AGEP in a Taiwanese population. Methods In this retrospective study, we reviewed patients diagnosed with AGEP with a EuroSCAR (RegiSCAR) validatio ..................More
  Use of extracellular extracts of lactic acid bacteria and bifidobacteria for the inhibition of dermatological pathogen Staphylococcus aureus
Yan Yan Hor, Min Tze Liong
DERMATOLOGICA SINICA 32 (2014) 141-147

Background/Objective Mycosis fungoides (MF) comprises the majority of cutaneous T-cell lymphomas (CTCLs). CTCLs associated with eosinophilia have a poor prognosis. Similar results were shown in white and black individuals with MF; however, the data on Asians is scant. In the past 10 years, few studies have provided profiles of the characteristics of MF patients in Taiwan. The purpose of this study was to investigate the demographic, clinicopathologic features, and prognosis of MF patients in Ta ..................More
  Mycosis fungoides in a referral center in central Taiwan: A retrospective case series and literature review
Kwei-Lan Liu, Jui-Lung Shen, Chii-Shuenn Yang, Yi-Ju Chen
DERMATOLOGICA SINICA 32 (2014) 148-153

Background/Objective Mycosis fungoides (MF) comprises the majority of cutaneous T-cell lymphomas (CTCLs). CTCLs associated with eosinophilia have a poor prognosis. Similar results were shown in white and black individuals with MF; however, the data on Asians is scant. In the past 10 years, few studies have provided profiles of the characteristics of MF patients in Taiwan. The purpose of this study was to investigate the demographic, clinicopathologic features, and prognosis of MF patients in Ta ..................More
  Brief Report
  Comparison of cryotherapy session intervals in the treatment of external genital warts
Belkız Uyar, Handan Sacar
DERMATOLOGICA SINICA 32 (2014) 154-156

A review of the literature found that the cryotherapy method used to treat external genital warts (EGWs) has been applied with varying intervals between sessions. However, no study has compared the intervals between sessions. The files of 312 patients who were diagnosed with genital warts and underwent cryotherapy were retrospectively reviewed. The patients were divided into two groups: 7–8 days between cryotherapy treatments and 14–21 days between cryotherapy treatments. The number of sessi ..................More
  Case Report
  Vulvitis circumscripta plasmacellularis in pre-existing lichen sclerosus
Han Su Kim, Heung Yeol Kim, Eun Joo Park, Kwang Ho Kim, Kwang Joong Kim
DERMATOLOGICA SINICA 32 (2014) 157-159

Vulvitis circumscripta plasmacellularis (VCP) is a rare, benign vulvar disorder that presents with erythematous patches and erosions. Patients with VCP usually experience vulvodynia, pruritus, or dyspareunia, which may cause severe discomfort. A 72-year-old woman presented with 10 years of vulvar pruritus and whitish patches on the labia minora and majora. A biopsy was performed on the labia minora and lichen sclerosus was diagnosed. Her condition improved after treatment with a topical steroid. ..................More
  The dermoscopic comma, zigzag, and bar code-like hairs: Markers of fungal infection of the hair follicles
Yu-Ting Lin, Yu-Chuan Li
DERMATOLOGICA SINICA 32 (2014) 160-163

Comma hair has been described as a specific dermoscopic feature of tinea capitis, however, it is not always present. Recognition of the additional dermoscopic features is therefore important. Furthermore, comma hair has never been shown to be applicable in fungal infection of the hair follicles on other parts of the body such as the eyebrows, axillary, or pubic areas. We encountered 13 Taiwanese patients who had been diagnosed with tinea capitis and evaluated their dermoscopic features using a n ..................More
  Malignant peripheral nerve sheath tumor arising from solitary neurofibroma
Pei-I Chung, Chang-Lin Chen, Yun-Ting Chang, Han-Nan Liu
DERMATOLOGICA SINICA 32 (2014) 164-168

Malignant peripheral nerve sheath tumors (MPNSTs) are rare sarcomas that are strongly associated with neurofibromatosis type I (NF-1). We describe a 71-year-old woman with no stigmata of neurofibromatosis, who presented with recurrent subcutaneous tumor on her left upper back. She received two excisional biopsies on the back of her trunk at our hospital and both pathology reports revealed neurofibromas. Three years after the last skin biopsy, a rapidly growing subcutaneous tumor emerged at the s ..................More
  Extragenital bullous lichen sclerosus: A case report and literature review
Yu-Hua Lee, Yu-Hung Wu
DERMATOLOGICA SINICA 32 (2014) 169-171

Lichen sclerosus (LS) is a chronic dermatosis characterized by atrophic white papules or plaques, most commonly occurring on the anogenital skin. Blisters have been rarely described developing in the background of extragenital LS. A 74-year-old woman with a 4-year history of sclerotic patches on the trunk showed a flaccid bulla on the lower back for 3 months. The histopathological finding of the skin biopsy was consistent with the diagnosis of bullous LS. In this paper, we present this uncommon ..................More
  Generalized syringotropic mycosis fungoides responsive to total skin electron beam therapy
Pei-Hsuan Lu, Shinn-Yn Lin, Lee-Yung Shih, Rosaline C.-Y. Hui, Tseng-tong Kuo
DERMATOLOGICA SINICA 32 (2014) 172-175

A case of syringotropic mycosis fungoides without internal organ involvement received total skin electron beam therapy (TSEBT) and evolved into poikilodermatous mycosis fungoides. Subsequent oral psoralen plus ultraviolet A (PUVA) therapy achieved complete remission. The value of TSEBT for syringotroopic mycosis fungoides is illustrated in this case. Keywords: poikilodermatous mycosis fungoides, syringotropic mycosis fungoides, total skin electron beam therapy ..................More
  Intraepidermal sebaceous carcinoma with superficial dermal invasion of the nipple
Kuo-Ming Chang
DERMATOLOGICA SINICA 32 (2014) 176-179

Sebaceous carcinoma (SC) is a rare malignant neoplasm usually presenting as an ocular lesion or, less commonly, an extraocular cutaneous lesion mostly on the head and neck, whereas it seldom found on other sites. We present a case of a 56-year-old woman with SC on her left nipple. To our knowledge, this is the second reported SC arising in the nipple, but may be the first case of SC of the nipple displaying predominance in intraepidermal proliferation with superficial dermal invasion—a very se ..................More
  A case of zoster sine herpete presenting with thoracic radicular pain diagnosed by polymerase chain reaction in skin exudate
Sang Hyeon Ku, Han Su Kim, Hyun Soo Kim, Eun Joo Park, Kwang Ho Kim, Kwang Joong Kim
DERMATOLOGICA SINICA 32 (2014) 180-182

Varicella zoster virus (VZV) can cause radicular pain in the absence of skin lesions; such cases are referred to as zoster sine herpete (ZSH) and are usually diagnosed by using serological assays or polymerase chain reaction (PCR). An effort is underway to detect VZV DNA in novel specimens rather than conventional samples (e.g., blood or cerebrospinal fluid) for PCR. There are two reports that PCR analysis in the exudate of the auricular skin can be a useful diagnostic tool for the diagnosis of ..................More
  Ticlopidine-induced subacute cutaneous lupus erythematosus: A case report and literature review
Yi-Ching Chen, Yu-Hung Wu
DERMATOLOGICA SINICA 32 (2014) 183-186

Many drugs have been reported to induce lupus in a minority of patients. Ticlopidine hydrochloride inhibits platelet aggregation and is widely used for the prevention of thrombosis. There have been only a few reports of ticlopidine-induced lupus. Here, we review 13 previously reported cases and describe the case of a 71-year-old man with ticlopidine-induced subacute cutaneous lupus erythematosus. His diagnosis was supported by the appearance of papulosquamous skin lesions on sun-exposed areas an ..................More
  Distinction of a postradiation atypical vascular lesion from cutaneous angiosarcoma in a patient with a history of breast cancer
Wen-Hui Chen, Bai-Yao Wu, Wei-Ming Wang
DERMATOLOGICA SINICA 32 (2014) 187-188

A 60-year-old woman with a medical history of infiltrative ductal carcinoma of the right breast underwent breast-conserving surgery and axillary lymph node dissection, followed by adjuvant chemotherapy, hormone therapy, and radiotherapy (conventional radiotherapy, 25 fractions for a total dose of 5000 cGy). Six years after treatment, asymptomatic skin eruptions on the right side of the chest and axilla were observed for 4 weeks. The patient was referred to the dermatology department for suspecte ..................More
  Treatment of multiple Bowen's disease with squamous cell and basal cell carcinomas with oral acitretin combined with excision
Yuan-Yuan Li, Ya-Li Song, Ben-Li Zhang, Li Zhang
DERMATOLOGICA SINICA 32 (2014) 189-190

A 61-year-old man presented with a 13-year history of multiple brown plaques all over his body. He had been feeding chickens for 16 years, and was often scratched or pecked in the upper limbs. Some lesions developed with a definite history of injury. Others around him who were feeding chickens did not have similar skin damage. The patient had suffered from several systemic diseases, such as chronic bronchitis and gastritis, for many years and took antibiotics and traditional Chinese medicine int ..................More
  Disseminated deep dermatophytosis caused by Trichophyton rubrum
Chun-Yu Cheng, Yi-Hsin Hsiao, Jui-Hung Ko
DERMATOLOGICA SINICA 32 (2014) 191-192

Dermatophytes are fungal pathogens that commonly cause superficial infections. In rare cases, a dermatophyte infection may be invasive, such as in Majocchi's granuloma, dermal and subcutaneous invasion, and disseminated or systemic infections. The clinical manifestations include subcutaneous nodules, small erythematous vesicles, cysts, discharging sinuses, or blastomycosis-like pyoderma.1 Here, we report a rare case of disseminated dermatophytosis. ..................More
  Desmoplastic cellular neurothekeoma
Wei-Ting Chang, Yu-Hung Wu, Nan-Lin Wu, Kuo-Ming Chang
DERMATOLOGICA SINICA 32 (2014) 193-194

A 39-year-old man presented for the evaluation and treatment of a 1-year history of an asymptomatic protruding nodule on his chin with slow progression in size (Figure 1A). He denied previous trauma or using any filler injections. He had no significant medical history. Physical examination revealed a firm skin-colored dome-shaped nodule with a telangiectatic surface on the chin. The clinical differential diagnosis included epidermal cysts and various adnexal neoplasms. The lesion was excised and ..................More
  Subungual clear cell acanthoma
Chun-Yu Cheng, Yung-Yi Lee, Jui-Hung Ko, Chih-Hsun Yang
DERMATOLOGICA SINICA 32 (2014) 195-196

A 70-year-old man presented with a painless papule on the nail bed of his right third finger, which had been present for 2 years. The patient did not have a history of nail trauma, nor did he have psoriasis or other inflammatory dermatosis. On physical examination there was a 4 × 4 mm erythematous to yellowish subungual keratotic papule with longitudinal splitting of the nail plate and ulceration on the nail bed of the right third finger (Figure 1A). The lesion was tender and firm in texture. D ..................More
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