Back issues No.1 - 1983 / Case Report  

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Familial Benign Chronic Pemphigus
S.Y. Sue, S.H. Jee, Y.F. Chao, D.K. Chen
Dermatol Sinica 1: 36-40, 1983

A 49-year-old male patient visited our O.P.D. because of intermittent erythematous vesicular plaques with crusts formation on both inguinal areas for more than 20 years. Recently, the same lesions were found on the neck, perianal area, both axillae and antecubital area. Histopathologic findings revealed hyper-keratosis with partial parakeratosis, hypergranulosis, acanthosis and rather extensive acantholysis with suprabasal blister formation. Many acantholytic cells are present in the acanthokytic lacunae with the appearance of a dilapidated brick wall. From the clinical symptoms and histopathologic findings, we diagnose this case to be familial benign chronic pemphigus.

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