Back issues No.2 - 1987 / Case Report  

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Mycosis Fungoides
Jaw-Shin Kao, Gwo-Shing Chen, Hsin-Su Yu
Dermatol Sinica 5: 109-115, 1987

Mycosis fungoides is a rare cutaneous T-cell lymphoma in Chinese. It can be divided into various stages according to the different clinical expressions. This report described a case of mycosis fungoides. The patient was a 60 years old male, who complained of a 5×5㎝brownish tumor in the left popliteal fossa and a few brownish plaques on both thighs and left axillary fossa. The Patient noted mild itching sensation over the above lesions occasionally, and no other specific sensation was noted. There was no local lymphadenopathy found. The above lesions had a history of about half a year. One histopathological examination, there were several Pautrier's microabscesses and epidermotropism, and many atpical lymphoid cells infiltrated in the upper and middle dermis. By immunohistochemical peroxidase-antiperoxidase staining technique, the labeling of OKT3, OKT4, and OKT8 T-lymphocyte surface antigens was demonstrated in most of the infiltrating cells in the dermis. The ratios of OKT positive cells to the total dermal infiltrating cells were as follows: OKT3(70%), OKT4(60%), OKT8(15%). Detail physical examination showed no evidence of metastasis. According to the above data, this case was diagnosed as a tumor stage of mycosis fungoides which was localized to the skin, and without metastasis to other tissue or organ.The patient received chemotherapy and PUVA photochemotherapy after the diagnosis. In the end of ten month follow-up, all the previous tumor and plaques had subsided and were replaced by hyperpigmented patches and macules. No recurrence was noted.

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