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Pemphigus Foliaceus with Cryptococcemia Caused by Cryptococcus Albidus
Sen-An Yang, Shiu-Ru Lin, Hsin-Su Yu, Hamm-Ming Sheu, Chein-Fang Peng
Dermatol Sinica 8: 31-35, 1990

We report a case of pemphigus foliaceus with cryptococcemia. A 45-year-old male patient suffered from gneralized erythroderma and the results of histopathology and DIF revald intrapidermal acantholysis & positive epidermal intercellular fluorescence. Pemphigus foliaceus was diagnosed. After receiving treatment, fever and leukocytosis were noted. Accidentally, cryptococcmia was found by blood cultrue. Besides, Cryptococcus Ag Latex test titer was> =1:128. After API 20c Aux profile recognition program, Cryptococcus albidus var. albidus was confirmed. Oral ketoconazol 400my qd was given for two weeks and Cryptococcus Ag titer decreased to 1:32. Two weeks later, cryptococcus Ag couldn't be detcted. We hope that opportunistic infection of cryptococcosis will be considered for immunosuppressed patients, so it can be diagnosed early and treated early.

   
   
 
 
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