Back issues No.4 - 1994 / Case Report  

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Pilomatricoma Associated with Bulla-like Dermal Change - Report of Five Cases -
Chien-Hsun Chen, Yue-Zon Kuang, Heng-Leong Chan
Dermatol Sinica 12: 201-208, 1994

Pilomatricoma is not an uncommon skin appendage tumor but it is unusual to see bulla-like formation in the overlying dermis. Clinically, this variant of pilomatricoma presents with a skin-colored to reddish protruding nodule with somewhat transparent bulla-like appearance, a hard nodule of pilomatricoma could be palpated underneath. Histopathology reveals fragmentation and marked attenuation of collagen fibers, decreasing number of elastic fibers, dilated lymphatic spaces, increased vascularity and vasodilatation in the severely edematous dermis. Anetodermic cutaneous change overlying pilomatricoma or pilomatricoma associated with bulla-like change have been used to describe similar lesions. We present five new cases of pilomatricomas associated with bulla-like dermal change and review the literature.

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