Back issues No.4 - 1995 / Case Report  

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Bullous Pemphigoid Occurring in Psoriasis
Shao-Yei Liu, Chen-Nai Wang, Heng-Leong Chan, Tseng-tong Kuo
Dermatol Sinica 13: 265-271, 1995

A 47-year-old man with a 21-year history of psoriasis was admitted to Chanf gung Memorial Hospital for an acute bullous eruption. About one month prior to admission, several small tense vesicles on the psoriatic plagues were noted on the trunk, which then rapidly spread to the extensor surfce of limbs. A biopsy specimen for hematoxylin-eosin stain revealed typical histologic findings of psoriasis.A subepidermal blister containing fibrin, leukocytes and eosinophils was also seen. Direct immunofluorescence study revealed linear IgG, IgA and C3 depositions along the dermoepidermal junction. A diagnosis of psoriasis with bullous pemphigoid was made. We report the first case of psoriasis vulgaris concurrent with bullous pemphigoid in Taiwan, and review the literatures.

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