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Pachyonychia Congenita
Shao-Yin Ma, Jia-Sheng Bair
Dermatol Sinica 14: 113-117, 1996

Pachyonychia congenita is a rare hereditary disease characterized mainly by nail hypertrophy and dyskeratoses of skin and mucous membrane. We herein report a case of male patient who has had nail dystrophy since childhood. Hyperkeratosis over soles and tiny keratotic papules are noted on dorsal aspect of fingers and toes. Biopsy from plantar lesions revealed marked orthokeratosis, acanthosis, hypergranulosis with coarse keratohyaline granules.

   
   
 
 
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