Back issues No.1 - 1997 / Case Report  

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Subcutaneous Spherulocystic Disease (Myospherulosis)-A Case Report-
Wu-Yen Lee, Shieh-Tai Liu, Yu-Wen Cheng, Ji-Chen Ho
Dermatol Sinica 15: 16-20, 1997

We present the case of a 47-year-old Taiwanese female with a solitary asymptomatic, and firm nodule in the right axilla for 8 months. Pathologic examination revealed cyst-like spaces in the subcutis. Numerous eosinphilic, pale, or light brown spherules were found within the cysts. Some of them aggregated together and were surrounded by an outer membrane, which later developed into a sac (parent body). They were not stained by Periodic Acid-Schiff's reaction (PAS) or Grocotl's Methenamine Silver nitrate (GMS). We believe the sperules were erythrocytes. It is important to avoid misdiagnosis of fungal or parasitic infection in such cases.

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