Back issues No.2 - 1997 / Case Report  

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Coexistent Bullous pemphigoid and Systemic Lupus Erythematosus: The Diagnostic Dilemma
Ching-Yuang Huang, Tsu-Chyang Chen
Dermatol Sinica 15: 81-86, 1997

A vesiculobullous eruption with clinical and histological features of bullous pemphigoid (BP) developed in a 74-year-old housewife with later proved systemic lupus erythematosus (SLE). The diagnosis of BP was based on indirect immunofluorescence studies on 1 M NaCl-split normal human skin showing high titer (1:320) IgG deposition along epidermal roof. This finding also discriminates between BP associated with SLE and other subepidermal bullous diseases, including bullous SLE, epidermolysis bullosa acquisita and dermatitis herpetiformis.

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