Papular Mucinosis with Carpal Tunnel Syndrome
Wen-Ling Huang, Hsu-Po Yeh, Shu-Fong Hsu, I-Ching Chu, Herng-Ming Leu
Dermatol Sinica 15: 121-126, 1997

A 48-year-old male patient presented with infiltrating erythematous papules and nodules accompanied with weaknes, hypoesthesia and pain of both hands for 1 month. Infiltrating plaques which were composed of groups of erythematous papules appeared on his scalp and the nape of the neck 1 week later. Histology showed mucin deposition in dermis which was positive with alcian blue stain at Ph 2.5 and metachromatically stained with toluidine blue. Nerve conduction velocity test and electromyography proved median nerve compression. Diagnosis of papular mucinosis with carpal tunnel syndrome was made. He was treated with prednisolone and cyclophosphamide for 2 weeks without response. However, skin lesions and carpal tunnel syndrome regressed at the same time 10 months later and no recurrence was noted after 6 years follow-up.