Back issues No.2 - 1998 / Case Report  

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Primary Cutaneous Adenoid Cystic Carcinoma—A Case Report and Review of the Literatur
Shu-Ching Hu, Tsen-Fang Tsai, Shiou-Haw Jee, Cheng-Hsiang Hsiao
Dermatol Sinica 16: 129-135, 1998

Adenoid cystic carcinoma (ACC) is a neoplasm of the major and minor salivary glands. Primary cutaneous adenoid cystic carcinoma is rare. We report a new case in a 68-year-old woman who presented a recurrent pea-sized intradermal nodule over her right inguinal area. Excisional biopsies were performed five times due to local recurrence. The histopathology of the last biopsy specimen showed uniform basaloid cells arranged in cribriform and tubular pattern. Basement membrane-like hyaline substance and mucin were seen either in the pseudolumen or surrounding the tubules and nests of tumor cells. There was no evidence of metastasis. Because of the multiple local recurrence, she was treated with wide excision with advancement flap.

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