Back issues No.2 - 1998 / Case Report  

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Solitary Myofibroma
Tzu-Jen Kuo, Wu-Yen Lee, Chao-Cheng Huang, Ji-Chen Ho
Dermatol Sinica 16: 141-146, 1998

A 50-year-old woman presented with a reddish, asymptomatic lump on her right dorsal hand for more than 20 years. She visited our OPD in April 1997. Clinically the base of the lesion was about 1-2 cm in diameter , firm , and hard but not fixed with deep tissue. Microscopically, it showed biphasic pattern of multiple peripheral nodules which were composed of elongated spindle cells and central vascular structure which was composed of hemangiopericytoma-like cells. Based on the unique histopathological findings, the diagnosis of solitary myofibroma was confirmed. The results of special stain and immunohistochemical studies including pan-actin ,vimetin and desmin stain were also consistent with the diagnosise

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