Back issues No.4 - 1999 / Case Report  

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Kimura's Disease
Shang-Wei Lin, Ming-Yuh Lee, Ho-Hsing Chang
Dermatol Sinica 17: 381-387, 1999

Kimura's disease is a rare inflammatory disorder that occurs predominantly in oriental young males. It typically presents as large subcutaneous masses of head and neck region. Kimura's disease has been confused with angiolymphoid hyperplasia with eosinophilia, from which it should be distinguished as a separate entity. We present a 72-year-old male patient who suffered from an asymptomatic subcutaneous swelling in his left preauricular area associated with left submandibular and upper cervical lymphadenopathy. Histopathologic examination of the skin lesion revealed several lymphoid follicles with germinal centers and infiltration of numerous eosinophils in the interfollicular region. Significant blood eosinophilia and high serum IgE level were detected. Under the diagnosis of Kimura's disease, he was treated with intralesional corticosteroid injection and the lesion resolved gradually.

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