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Combined Nevus-Report of Two Cases-
Kuo-Liang Cheng, Woan-Ruoh Lee
Dermatol Sinica 18: 245-249, 2000

Combined nevus is a unique pigmented lesion of mixed cytological patters. Among the usual attributes are ordinary (nevocellular) nevus cells, pigmented spindle cells, dendritic cells of blue nevus and occasionally epitheloid and spindle cells of Spitz nevus. It tends to be misdiagnosed for its common nevus appearance and its being indistinguishable from other melanocytic lesions without recognition of distinctive phenotypic expressions. We herein report two cases of variants of combined nevi. Microscopically, the first case shows a pattern of small congenital melanocytic nevus cells intermixed with plump, pigmented spindle cells, and the other case has a combination of compound nevocytic nevus cells with characteristic pigmented dendritic cells of blue nevi. Our cases like the overwhelming majorities of the previous reported cases, behave as a benign fashion without local recurrence or metastases during one year of clinical follow-up.

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