Back issues No.3 - 2001 / Original Study  

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Allergic Contact Dermatitis of Paraphenylenediamine
Chii-Shyan Wang, Mei-Ping Tseng, Chee-Ching Sun
Dermatol Sinica 19: 184-189, 2001

Para-phenylenediamine (PPD), a primary intermediate in hair dye, is a potent contact allergen and a common cause of allergic contact dermatitis in hairdressers. We report the results of patch testing with PPD in National Taiwan University Hospital in the past 22 years. 115 (3.46%) of the total patch-tested 3322 patients were positive to PPD. The commonest sites of dermatitis were the face (41.5%) and the hand (28.3%). Hands of hairdressers and face of non-hairdressers were the commonest site of allergic dermatitis of PPD. Hairdressers had an increased risk to be allergic to PPD (odds ratio=20.4). We also review the literatures about allergic contact dermatitis to PPD.

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