Back issues No.2 - 2002 / Original Study  

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Patch Testing with Fragrance Mix: a 13-year Experience
Hsuan-Hsian Chen Chee-Ching Sun Mei-Ping Tseng
Dermatol Sinica 20: 90-96, 2002

Fragrances are widely encountered in our living environment and are known to be a common cause of allergic contact dermatitis. We have reviewed our patch test data from 1987 to 1999 to establish the pattern of fragrance allergy. During this period, 1,993 patients were patch tested with the European standard series. The positive rate to the fragrance mix was 8.38%. The incidence of fragrance mix allergy was increasing throughout the study period (ρ=0.028). Men were 6.4 years older than that of women (ρ<0.05). Besides nickel sulfate, balsam of Peru, medicaments, p-phenylenediamine, and colophony were the most common allergens in fragrance-mix-allergic patients. The most common areas of dermatitis were the face (32.8%) and the hand (18.8%). The most common profession of both the male and female participants in the fragrance-mix-allergic study was office worker (21.6%). However, the most common occupation held by the female patients was office worker (26.4%), while that by the male patients were agriculturist/construction worker (13.7%/13.7%). Patients with atopic history did not show any effect in terms of incidence of fragrance allergy.

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