Back issues No.3 - 2002 / Original Study  

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The Study of Cutaneous Malignancies in Renal Transplant Recipients-Southern Taiwan Experience
Wen-Wei-Feng Ji-Chen Ho Chao-Hua Chuang Hwai-Ho Hsieh
Dermatol Sinica 20: 169-179, 2002

Skin cancer is the most common cancer among renal-transplant recipients in Western studies, but in Taiwan the related information appears limited. We studied a population-based cohort of 286 renal-transplant recipients in southern Taiwan between 1981 and 1999, in order to identify the incidence and distribution of cancers. Sixteen of the 286 renal-transplant recipients developed malignancies. The distribution of malignancies deriving from renal transplant recipients in southern Taiwan appears to be totally different from that in Western countries. The most common type of cancer in our study was bladder cancer, and two patients experienced Kaposi's sarcoma, and one revealed lymphoma cutis, although there were no cases of either squamous-cell carcinoma or basal-cell carcinoma. Being female and being older rather than younger at time of renal transplantation appear to be the only two risk factors for malignancy formation. Here we first report Kaposi's sarcoma and lymphoma cutis in renal transplant recipients in Taiwan. The incidence may be associated with long-term use of immunosuppressive agents very strongly. Clinicians should continually be on guard in order to be alert for the potential oncogenic complications of immunosuppressive agents.

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