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Lipodermatosclerosis Complicating Deep Vein Thrombosis—A Case Treated with Stanozolol—
Li-Na Tung Hsin-Chi Chen Hsin-Yi Su
Dermatol Sinica 20: 234-240, 2002

A 21-year-old male had noted two slowly enlarging, hyperpigmented sclerotic patches on his left leg and ankle respectively for more than one year; in the meantime, the lesion on the ankle progressed into a poor-healing deep ulcer gradually. He had a history of deep vein thrombosis of left thigh occurring about three years ago. The diagnosis of lipodermatosclerosis was established on the basis of clinical manifestation, histopathology and immunofluorescence examination. After six weeks of stanozolol therapy, the ulcer shrinked obviously, and the sclerotic patches became less indurated and decreased in size. In addition, the plasma fibrinogen level was also decreased significantly. However, because of the sustainedly elevated serum transaminase level, we discontinued the oral stanozolol. Three weeks later, the liver function recovered, but the plasma fibrinogen level elevated again.

   
   
 
 
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