Back issues No.2 - 2003 / Case Report  

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Amelanotic Melanoma
Kun-Wei Chiu, Pei-Lin Chung
Dermatol Sinica 21 : 187-191, 2003

Cutaneous amelanotic melanoma is easily confused with some benign or malignant skin lesions in clinical. It can not be diagnosed by physician at first visit. We report a 44-year-old man, who suffered from a non-healing, progressively enlarging ulcer located on right great toe for 3 months. Histopathologically, it shows infiltrating nests or trabecules of pleomorphic cells in dermis and subcutaneous tissue. Immunohistochemical study reveals positive staining for HMB-45. Radionuclear study shows metastasis of right inguinal lymph node. The patient received amputation surgery of right great toe and right inguinal lymph node dissection. We review literatures and report this uncommon case to call attention for this condition.

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