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Sporotrichosis-like Dermatosis Caused by Mycobacterium avium complex—A Case Report
Guan-Yu Chen, Jing-Jou Yan, Heng-Leong Chan, Hamm-Ming Sheu
Dermatol Sinica 22 : 46-52, 2004

We report a case of cutaneous atypical mycobacteriosis in a 30-year-old female due to Mycobacterium avium complex. The skin lesions were three enlarging subcutaneous tender nodules with ulceration over right thigh and knee in a sporotrichoid pattern. Histopathological examination revealed irregular epidermal hyperplasia with a dense mixed cell infiltrate composed of neutrophils, lymphocytes, plasma cells, eosinophils and multi-nucleated giant cells. The Gomori methenamine silver stain fails to detect spores in the dermis. The Acid-fast stain and Gram stain were also negative. Under the impression of sporotrichosis, the patient received oral potassium iodide 3 g/day for 1 month. However, her cutaneous lesions became worse gradually. The polymerase chain reaction-based method suggested an infection caused by an M. avium complex. Patient’s skin lesions completely cured after receiving doxycycline 200 mg/day for one and half a year. There is no evidence of recurrence 8 months after stopping medication.

   
   
 
 
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