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Linear Lupus Erythematosus Profundus on the Scalp Following the Lines of Blaschko in an Adult
Chun-Ping Wu , Tsen-Fang Tsai
Dermatol Sinica 22 : 166-172, 2004

The lines of Blaschko describe distribution patterns which may represent embryologic development pathways. The distribution may be followed by some congenital and acquired skin disorders. Lupus erythematosus profundus(LEP) is a rare disease characterized by deep nodules and plaques, most commonly localized on the buttocks, arms, thighs and face. There is only one reported case of LEP on the scalp following the lines of Blaschko. We herein report the second case. The patient was a 21-year-old female presenting with a spiral-shaped alopecia on the scalp for one year. Skin biopsy taken from the lesion showed fat degeneration with mucin deposit and perieccrine infiltration of mononuclear cells. She was treated with oral hydroxychloroquine(200 mg/day) for 7 weeks. Complete regrowth of hair on the previous alopecic area was noted in the following one year.

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