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Linear Lupus Erythematosus Profundus:-Report of a Case and Review of the Literature
Jeng-Wei Tjiu , Chia-Yu Chu
Dermatol Sinica 22 : 221-226, 2004

Lupus erythematosus profundus (LEP) is a rare entity characterized by erythematous or flesh-colored deep nodules and plaques, with a predilection for the buttocks, arms, thighs and face. There are only 4 reported cases of linear variant of LEP in the English literature. We herein report another case of linear LEP. The patient was a 26-year-old female who presented with a linear indurated erythematous plaque along the left arm to her left palm. Skin biopsy taken from the lesion showed lymphocytic panniculitis with hyaline fat necrosis. Direct immunofluorescence study revealed granular depositions of IgM, C3 and C1q along the basement membrane. She was treated with oral hydroxychloroquine, topical corticosteroids and topical tacrolimus ointment. Control of the disease activity was achieved after treatment for nine months.

   
   
 
 
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