Back issues No.2 - 2005 / Case Report  

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Cutaneous Metastasis from Laryngeal Atypical Carcinoid
Mei-Ying Chen, Ying-Jui Chang, Pei-Wei Shueng, Cheng-Hsiang Hsiao, Yao- Peng Shu , Lin-Hui Su, Yu-Ling Hsu
Dermatol Sinica 23:96-100,2005

Carcinoid tumors are primarily regarded as tumors of the appendix and small intestine, but they have been shown to arise from almost any tissue derived from the primitive gut, including its respiratory diverticulum. Cutaneous metastasis from carcinoid tumors is distinctly rare, and only a few cases have been documented. In this report, we present one case of laryngeal atypical carcinoid tumor with skin metastasis. The diagnosis of metastastic carcinoid to the skin was established by clinical history, histopathology and immunocytochemical methods including positive stains of chromogranin, NSE, synaptophysin and cytokeratin AE1/AE3, etc.. To our knowledge, this is the first reported case of a laryngeal atypical carcinoid with skin metastasis in Taiwan[JH1]. We disclose the aggravated behavior of the laryngeal atypical carcinoid tumor and remind dermatologists to be aware of the possibility of cutaneous metastasis, even if the primary tumor is a carcinoid.

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