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Malignant Fibrous Histiocytoma Occurring in the Digit
Ya-Jing Hsu Yu-Ling Hsu Ying-Jui Chang Cheng-Hsiang Hsiao Lin-Hui Su Tsung-Hua Tsai
Dermatol Sinica 27: 68-71, 2009

A 65-year-old Taiwanese female initially
presented an 1-year history of experiencing
an asymptomatic dark reddish subungual
mass on the left thumb (Fig. 1A). The
patient’s medical history included diabetes
mellitus, hypertension, coronary arterial disease,
and a right hemiparesis resulting from
an intracerebral hemorrhage ten years prior.
No history of trauma, irradiation, or chemical
exposure to her hands was disclosed. A
skin biopsy from the periphery of the lesion
was performed and histopathologic examination
revealed multinucleated giant cells and
mononuclear inflammatory cells dispersed
in the dermis (Fig. 1B, C). A diagnosis of giant
cell tumor of tendon sheath was made to
the patient. The patient preferred to preserve
the function of the left thumb and undergo a
conservative course of treatment so the tumor
was removed by treatment with a carbon
dioxide laser. At that point the patient discontinued
further follow-up.

   
   
 
 
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