Back issues No.1 - 2013 / Case Report  

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Ossifying fibromyxoid tumor – A case report
Chin-Chun Chen, Tsung-Ming Tsai, Tzu-Hsuan Liu, Kuo-Chia Yang, Hui-Ju Yang, Tzu-Cheng Su, Pei-Yi Chu

Ossifying fibromyxoid tumor (OFMT) is a rare soft tissue tumor of uncertain histogenesis, occurring predominantly in deep soft tissues of the extremities. Typically, OFMT presents in adults on the extremities or trunk, as a deep soft tissue mass. Less appreciated is the fact that OFMT may also present as a mass in the superficial subcutis or dermis. We herein report a female who presented with an asymptomatic subcutaneous nodule on the left thigh for 3 years, and who was diagnosed as having typical ossifying fibromyxoid tumor, by unique histopathologic and immunohistochemical studies. Most reported cases have pursued a benign clinical course. However, recent literature emphasized the existence of morphologically atypical and clinically malignant cases of OFMTs. Pathologic criteria for malignancy have been proposed, and reclassification of these tumors as tumors of intermediate malignancy, raise our attention while coping with OFMT clinically.

Keywords: intermediate malignancy, soft tissue tumor, ossifying fibromyxoid tumor

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