Back issues No.1 - 2014 / Case Report  

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Overlap syndrome of type Wong variant dermatomyositis and rheumatoid arthritis
Yen-Jen Wang, Yu-Hung Wu, Tien-Ling Chen

Wong type dermatomyositis describes a small group of patients with dermatomyositis clinically presented with pityriasis rubra pilaris-like eruptions, including diffuse palmoplantar hyperkeratosis and follicular hyperkeratosis. Histopathologic findings include follicular hyperkeratosis and arrector pili myositis. There have been 20 cases reported since Wong's large series. We report a 56-year-old male with overlap syndrome of Wong type dermatomyositis and rheumatoid arthritis. He also fulfilled the criteria of anti-tRNA synthetase syndrome due to the presence of anti-Jo-1 antibody and clinical features of both rheumatoid arthritis and myositis. No internal malignancy was found after a complete systemic survey and within 1 year follow-up period. There was a good response to oral steroid therapy.

Keywords: anti-Jo-1 antibody, dermatomyositis, overlap syndrome, pityriasis rubra pilaris, rheumatoid arthritis

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